Downregulation of membrane-bound angiotensin converting enzyme 2 (ACE2) receptor has a pivotal role in COVID-19 immunopathology
C Vieira, L Nery, L Martins, L Jabour, R Dias… - Current drug …, 2021 - ingentaconnect.com
Background: The Coronavirus Disease 2019 (COVID-19) is becoming the major health
issue in recent human history with thousands of deaths and millions of cases worldwide …
issue in recent human history with thousands of deaths and millions of cases worldwide …
Interaction of SARS-CoV-2 and other coronavirus with ACE (angiotensin-converting enzyme)-2 as their main receptor: therapeutic implications
AM Davidson, J Wysocki, D Batlle - Hypertension, 2020 - Am Heart Assoc
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 originated from Wuhan,
China, in December 2019 and rapidly spread to other areas worldwide. Since then …
China, in December 2019 and rapidly spread to other areas worldwide. Since then …
[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions
The novel corona virus disease has shaken the entire world with its deadly effects and rapid
transmission rates, posing a significant challenge to the healthcare authorities to develop …
transmission rates, posing a significant challenge to the healthcare authorities to develop …
Angiotensin-converting enzyme 2 (ACE2): COVID 19 gate way to multiple organ failure syndromes
Background Globally, the current medical emergency for novel coronavirus 2019 (COVID-
19) leads to respiratory distress syndrome and death. Purpose This review highlighted the …
19) leads to respiratory distress syndrome and death. Purpose This review highlighted the …
Angiotensin converting enzyme-2 as therapeutic target in COVID-19
The pandemic of coronavirus disease 2019 (COVID-19) is a global health emergency that
poses a significant threat to world people's health. This outbreak causes major challenges to …
poses a significant threat to world people's health. This outbreak causes major challenges to …
[HTML][HTML] Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy
J Zhang, KM Tecson, PA McCullough - Reviews in cardiovascular …, 2020 - imrpress.com
Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019
(COVID-19). There is growing evidence to suggest that the angiotensin converting enzyme 2 …
(COVID-19). There is growing evidence to suggest that the angiotensin converting enzyme 2 …
ACE2: the molecular doorway to SARS-CoV-2
MM Medina-Enríquez, S Lopez-León… - Cell & bioscience, 2020 - Springer
The angiotensin-converting enzyme 2 (ACE2) is the host functional receptor for the new
virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different …
virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different …
Expression of ACE2, soluble ACE2, angiotensin I, angiotensin II and angiotensin-(1-7) is modulated in COVID-19 patients
The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …
Is the endothelium the missing link in the pathophysiology and treatment of COVID-19 complications?
P Castro, M Palomo, AB Moreno-Castaño… - … drugs and therapy, 2022 - Springer
Patients with COVID-19 present a wide spectrum of disease severity, from asymptomatic
cases in the majority to serious disease leading to critical care and even death. Clinically …
cases in the majority to serious disease leading to critical care and even death. Clinically …