An open-label randomized controlled trial evaluating the efficacy of chloroquine/hydroxychloroquine in severe COVID-19 patients

Á Réa-Neto, RS Bernardelli, BMD Câmara, FB Reese… - Scientific reports, 2021 - nature.com
Despite several studies designed to evaluate the efficacy of chloroquine and
hydroxychloroquine in the treatment of coronavirus disease 2019 (COVID-19), there is still …

Hydroxychloroquine: A review of its safety and efficacy in COVID-19

RH Karia, S Nagraj, I Gupta, A Barua… - Journal of family …, 2021 - journals.lww.com
SARS-CoV-2 is a novel virus that has infected millions of people across the world. Given the
compelling need to develop a therapeutic strategy, hydroxychloroquine has been advocated …

Hydroxychloroquine in the treatment of COVID-19 disease: A systematic review and meta-analysis

A Manzo-Toledo, R Torres-Rosas… - Medical Journal of …, 2021 - mji.ui.ac.id
BACKGROUND Given the urgency of finding a specific treatment for coronavirus disease
2019 (COVID-19), several approaches have been carried out, including the use of …

The rise and fall of chloroquine/hydroxychloroquine as compassionate therapy of COVID-19

E Manivannan, C Karthikeyan… - Frontiers in …, 2021 - frontiersin.org
The emergence and rapid spread of novel coronavirus disease (COVID-19) has posed a
serious challenge to global public health in 2020. The speed of this viral spread together …

Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19

A Cortegiani, M Ippolito, G Ingoglia, P Iozzo… - Journal of critical …, 2020 - Elsevier
Purpose To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for
treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE …

Systematic review and pharmacological considerations for chloroquine and its analogs in the treatment for COVID-19

H Peng, Z Chen, Y Wang, S Ren, T Xu, X Lai… - Frontiers in …, 2020 - frontiersin.org
COVID-19 has been announced pandemic by WHO and over 17,000,000 people infected
(Till April 21st 2020). The disease is currently under control in China, with a curative rate of …

A pharmacological perspective of chloroquine in SARS-CoV-2 infection: An old drug for the fight against a new coronavirus?

TJ Oscanoa, R Romero-Ortuno, A Carvajal… - International journal of …, 2020 - Elsevier
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is having serious consequences on …

[HTML][HTML] No clinical benefit in mortality associated with hydroxychloroquine treatment in patients with COVID-19

K Sands, R Wenzel, L McLean, K Korwek… - International Journal of …, 2021 - Elsevier
Background The use of hydroxychloroquine (HCQ), with or without concurrent administration
of azithromycin (AZM), for treatment of COVID-19 has received considerable attention. The …

Safety of short-term treatments with oral chloroquine and hydroxychloroquine in patients with and without COVID-19: a systematic review

S Marin, A Martin Val, M Bosch Peligero… - Pharmaceuticals, 2022 - mdpi.com
Chloroquine (CQ) and hydroxychloroquine (HCQ) have recently become the focus of global
attention as possible treatments for Coronavirus Disease 2019 (COVID-19). The current …

[HTML][HTML] The role of Hydroxychloroquine in the age of COVID-19: a periodic systematic review and meta-analysis

A Shamshirian, A Hessami, K Heydari… - 2020 - europepmc.org
Background Coronavirus Disease 2019 (COVID-19) has become a major global issue with
rising the number of infected individuals and mortality in recent months. Among all …