E Ha, SC Bae, K Kim - Annals of the rheumatic diseases, 2021 - ard.bmj.com
Objectives Nearly 110 susceptibility loci for rheumatoid arthritis (RA) with modest effect sizes have been identified by population-based genetic association studies, suggesting a large …
G Orozco, A Barton - Expert Review of Clinical Immunology, 2010 - Taylor & Francis
Rheumatoid arthritis (RA) is a complex disease, meaning that multiple genetic variants, environmental factors and random events interact to trigger pathological pathways. Although …
Y Nagai, T Imanishi - Database, 2013 - academic.oup.com
Rheumatoid arthritis (RA) is a common autoimmune inflammatory disease of the joints and is caused by both genetic and environmental factors. In the past six years, genome-wide …
S Negi, G Juyal, S Senapati, P Prasad… - Arthritis & …, 2013 - Wiley Online Library
Objective Genome‐wide association studies (GWAS) and their subsequent meta‐analyses have changed the landscape of genetics in rheumatoid arthritis (RA) by uncovering several …
L Jiang, J Yin, L Ye, J Yang, G Hemani… - Arthritis & …, 2014 - Wiley Online Library
Objective To investigate differences in genetic risk factors for rheumatoid arthritis (RA) in Han Chinese as compared with Europeans. Methods A genome‐wide association study was …
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
Genome-wide association studies (GWASs) have been used to great effect to identify genetic susceptibility loci for complex disease. A series of GWAS and meta-analyses have …
Background Genetic factors have a substantial role in determining development of rheumatoid arthritis (RA), and are likely to account for 50–60% of disease susceptibility …
FY Deng, SF Lei, H Zhu, YH Zhang… - The Journal of …, 2013 - jrheum.org
Objective. Extensive association analyses including genome-wide association studies (GWAS) and powerful metaanalysis studies have identified a long list of loci associated with …