Laboratory findings are an essential part of the diagnostic approach to organic acidemias. In
most organic acidemias, metabolism of glucose, ketone bodies, and ammonia is deranged …

Organic acidemias are disorders of intermediary metabolism that lead to accumulation of
organic acids in biologic fluids, disturb acid-base balance, and derange intracellular …

Organic acid disorders are inherited metabolic disorders in which organic acids accumulate
in tissues and biological fluids of affected individuals. Classical organic acidurias include …

Neurological manifestations are very common and can be the leading and/or presenting
feature in organic acid disorders, sometimes in the absence of metabolic derangement …

Organic acid analysis is a powerful technique in the diagnosis of inborn errors of
metabolism. Since the development of the technique over twenty-five years ago, it has …

An article about organic acidemias is a new addition to an outline of inborn errors of
metabolism. Its inclusion follows the application of new laboratory methods to the …

The Inborn Errors of Metabolism and Neurology Services of the King Faisal Specialist
Hospital and Research Centre (KFSH&RC) and Armed Forces Hospital have received more …

Disease characteristics. The term" organic acidemia" or" organic aciduria"(OA) applies to a
group of disorders characterized by the excretion of non-amino organic acids in urine. Most …

Organic acidurias (synonym, organic acid disorders, OADs) are a heterogenous group of
inherited metabolic diseases delineated with the implementation of gas …

BACKGROUND: Organic acidurias or organic acidemias are inherited metabolic disorders
in which organic acids (carboxylic acids) accumulate in tissues and physiologic fluids of …