5-Hydroxytryptamine 1A receptors, major depression, and suicidal behavior

W Pitchot, M Hansenne, E Pinto, J Reggers, S Fuchs… - Biological …, 2005 - Elsevier
BACKGROUND: Several lines of evidence suggest a clear relationship between serotonin
(5-hydroxytryptamine, 5-HT) hypoactivity and suicidal behavior across several psychiatric …

Serotonin receptors in suicide victims with major depression

CA Stockmeier, GE Dilley, LA Shapiro… - …, 1997 - Elsevier
Serotonin1A (5-HT1A) and serotonin2A (5-HT2A) receptors in the brain have been
implicated in the pathophysiology of suicide. Brain samples were collected at autopsy from …

Interaction between the serotonergic system and HPA and HPT axes in patients with major depression: implications for pathogenesis of suicidal behavior

F Duval, MC Mokrani, J Monreal, T Weiss… - Dialogues in clinical …, 2002 - Taylor & Francis
Disturbances in the serotonin (5-hydroxytryptamine, 5-HT) system constitute the
neurobiological abnormality most consistently associated with suicide. This abnormality …

Quantification of 5-HT1A and 5-HT2A receptor Binding in Depressed Suicide Attempters and Non-Attempters

JJ Mann, AV Metts, RT Ogden, CA Mathis… - Archives of Suicide …, 2019 - Taylor & Francis
Objective: To determine serotonin system abnormalities related to major depression or
previous suicidal behavior. Methods:[11C] WAY100635,[18F] altanserin and positron …

The flesinoxan 5-HT1A receptor challenge in major depression and suicidal behavior

W Pitchot, M Ansseau, AG Moreno… - …, 1995 - thieme-connect.com
The prevailing neurochemical theory about biological correlates of suicidal behavior focuses
on the serotonergic system. In this study, we assessed the Cortisol, ACTH, CH, prolactin and …

5-HT1A receptor binding sites in post-mortem brain samples from depressed suicides and controls

S Lowther, F De Paermentier, SC Cheetham… - Journal of affective …, 1997 - Elsevier
5-HT1A receptor binding sites were measured, by saturation binding with [3H] 8-OH-DPAT,
in frontal and occipital cortex, hippocampus and amygdala obtained at post-mortem …

Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects

H Anisman, L Du, M Palkovits, G Faludi… - Journal of Psychiatry and …, 2008 - jpn.ca
Objective: Studies comparing people suffering from depression who commited suicide with
control subjects have yielded inconsistent results regarding serotonin (5-HT) involvement in …

Brain 5-HT1 binding sites in depressed suicides

SC Cheetham, MR Crompton, CLE Katona… - …, 1990 - Springer
HT 1 and 5-HT 1A binding sites were measured in brain tissue obtained at postmortem from
19 suicides, with definite evidence of depression, and 19 sex and age-matched controls …

Higher Expression of Serotonin 5-HT2A Receptors in the Postmortem Brains of Teenage Suicide Victims

GN Pandey, Y Dwivedi, HS Rizavi… - American Journal of …, 2002 - Am Psychiatric Assoc
OBJECTIVE: Abnormalities of serotonin (5-HT) receptor subtypes have been observed in the
postmortem brains of adult suicide victims; however, their role in teenage suicide is …

5-HT1D and 5-HT1E/1F binding sites in depressed suicides: increased 5-HT1D binding in globus pallidus but not cortex

S Lowther, CLE Katona, MR Crompton… - Molecular …, 1997 - nature.com
HT 1D and 5-HT 1E/1F receptor binding sites were measured in brain samples obtained at
post-mortem from suicide victims with a firm retrospective diagnosis of depression, and …