[HTML][HTML] Multifactorial pathogenesis of osteoporosis and the role of genes of canonical wnt-signaling pathway

EA Mailyan - Osteoporosis and Bone Diseases, 2015 - osteo-endojournals.ru
Nowadays, multifactorial nature of osteoporosis does not raise any doubts. Besides, it
should be noted that about 90% disease cases are determined genetically. In 1990-sa …

Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity

Y Xiao, J Cui, YX Li, YH Shi, B Wang, GW Le, ZP Wang - Nutrition, 2011 - Elsevier
OBJECTIVE: The present study examined impacts of dyslipidemic high-fat diet on the bone
antioxidant system and bone metabolism in growing mice. Furthermore, the relationship was …

Progress of Wnt signaling pathway in osteoporosis

Y Gao, N Chen, Z Fu, Q Zhang - Biomolecules, 2023 - mdpi.com
Osteoporosis, one of the serious health diseases, involves bone mass loss, bone density
diminishing, and degeneration of bone microstructure, which is accompanied by a tendency …

Fatty acid metabolism by the osteoblast

P Kushwaha, MJ Wolfgang, RC Riddle - Bone, 2018 - Elsevier
The emergence of bone as an endocrine organ able to influence whole body metabolism,
together with comorbid epidemics of obesity, diabetes, and osteoporosis, have prompted a …

Association between Metabolic Syndrome and the Musculoskeletal System

W Shi, Q Zhang - Nutrients, 2023 - mdpi.com
Metabolic syndrome (MetS) and osteoporosis are chronic health disorders worldwide. MetS
is a condition characterized by clinical features like abdominal obesity, hyperglycemia …

Is obesity in women protective against osteoporosis?

S Migliaccio, EA Greco, R Fornari… - … syndrome and obesity …, 2011 - Taylor & Francis
The belief that obesity is protective against osteoporosis has recently come into question.
The latest epidemiologic and clinical studies have shown that a high level of fat mass might …

The pathophysiology of osteoporosis in obesity and type 2 diabetes in aging women and men: The mechanisms and roles of increased bone marrow adiposity

D Ali, M Tencerova, F Figeac, M Kassem… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis is defined as a systemic skeletal disease characterized by decreased bone
mass and micro-architectural deterioration leading to increased fracture risk. Osteoporosis …

Obesity and bone: a complex relationship

G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …

Wnt/β-catenin signaling in osteoblasts regulates global energy metabolism

Q Yao, C Yu, X Zhang, K Zhang, J Guo, L Song - Bone, 2017 - Elsevier
Obesity, diabetes and osteoporosis have become a major public heath burden, and
understanding the underlying mechanisms of these pathophysiological process will benefit …

Regulation of bone mass in inflammatory diseases

G Adami - Best Practice & Research Clinical Endocrinology & …, 2022 - Elsevier
Inflammation is among the major determinants of bone loss in chronic disease and aging.
Bone metabolism is radically affected by inflammation with consequent bone loss and …