The RNA and DNA tumor viruses have made fundamental contributions to two major areas of cancer research. Viruses were vital, first, to the discovery and analysis of cellular growth …
The study of cancer is incomplete without taking into consideration of tumorigenic viruses. Initially, searches for human cancer viruses were fruitless despite an expansion of our …
JB Liao - The Yale journal of biology and medicine, 2006 - ncbi.nlm.nih.gov
An estimated 15 percent of all human cancers worldwide may be attributed to viruses [1], representing a significant portion of the global cancer burden. Both DNA and RNA viruses …
Highlights•Viral infections cause approximately 12% of all human cancers.•Viral cancers represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …
ME McLaughlin-Drubin, K Munger - … Acta (BBA)-Molecular Basis of Disease, 2008 - Elsevier
It is estimated that viral infections contribute to 15–20% of all human cancers. As obligatory intracellular parasites, viruses encode proteins that reprogram host cellular signaling …
D Martin, JS Gutkind - Oncogene, 2008 - nature.com
The study of acute-transforming retroviruses and their oncogenes and of the multiple mechanisms deployed by DNA viruses to circumvent the growth-suppressive and …
Viruses are the intracellular pathogens that reproduce only in the living cell and manipulate the cellular machinery to produce more viruses. Viral replications can affect cellular genes of …
The impact of basic research on oncology has been particularly impressive in the recent search for the cause of malignancy. Equally impressive is our appreciation of the cause of …
Can the cancer cell be understood? Since no one can yet explain how a normal cell controls its growth, it may seem foolhardy to think the ab normal rules governing the growth of a …