[HTML][HTML] Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to genomic approaches

AT Marques, JMB Vítor, A Santos… - Microbial …, 2020 - microbiologyresearch.org
For a long time Helicobacter pylori infections have been treated using the macrolide
antibiotic, clarithromycin. Clarithromycin resistance is increasing worldwide and is the most …

[HTML][HTML] Primary clarithromycin resistance to Helicobacter pylori: Is this the main reason for triple therapy failure?

F Giorgio, M Principi, V De Francesco… - World journal of …, 2013 - ncbi.nlm.nih.gov
Conventional triple therapies for Helicobacter pylori (H. pylori) eradication have recently
shown a disappointing reduction in effectiveness in many countries. The main reason for …

Phenotypic and genotypic Helicobacter pylori clarithromycin resistance and therapeutic outcome: benefits and limits

V De Francesco, A Zullo, E Ierardi… - Journal of …, 2010 - academic.oup.com
Introduction Primary clarithromycin resistance is increasing worldwide, and it has been
regarded as the main factor reducing the efficacy of Helicobacter pylori therapy. However …

Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy

V De Francesco, M Margiotta, A Zullo… - Journal of …, 2007 - academic.oup.com
Objectives The frequency of primary clarithromycin resistance in Helicobacter pylori strains
is increasing worldwide, and its presence significantly reduces the treatment efficacy of …

[HTML][HTML] Helicobacter pylori resistance to antibiotics in 2014 in France detected by phenotypic and genotypic methods

A Ducournau, L Bénéjat, E Sifré, E Bessède… - Clinical Microbiology …, 2016 - Elsevier
A large survey of antimicrobial resistance of Helicobacter pylori was performed in France in
2014: 984 patients were enrolled by 75 gastroenterologists all over the country. Among the …

Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing

TT Binh, S Shiota, R Suzuki, M Matsuda… - Journal of …, 2014 - academic.oup.com
Objectives Resistance to clarithromycin is the most important factor causing failure of
Helicobacter pylori eradication. Although clarithromycin resistance is mainly associated with …

Rapid detection of clarithromycin resistance in Helicobacter pylori using a PCR-based denaturing HPLC assay

P Posteraro, G Branca, M Sanguinetti… - Journal of …, 2006 - academic.oup.com
Objectives: We evaluated a new approach for the rapid detection of clarithromycin
resistance in Helicobacter pylori, based on PCR and denaturing HPLC (DHPLC). Methods …

Prevalence of Helicobacter pylori resistance to clarithromycin in Tunisia

L Chtourou, M Moalla, B Mnif… - Journal of Medical …, 2022 - microbiologyresearch.org
Background. Helicobacter pylori (H. pylori) resistance to clarithromycin is increasing
worldwide. Data on the prevalence of H. pylori resistance are limited in Tunisia. Gap …

[PDF][PDF] Primary clarithromycin resistance in Helicobacter pylori: The multicentric Italian clarithromycin resistance observational (MICRO) study

V De Francesco, F Giorgio, E Ierardi, M Zotti… - J Gastrointestin …, 2011 - researchgate.net
Background. Primary clarithromycin resistance markedly reduces Helicobacter pylori
eradication rate following standard therapies. Prevalence of primary clarithromycin …

Change of point mutations in Helicobacter pylori rRNA associated with clarithromycin resistance in Italy

V De Francesco, A Zullo, F Giorgio… - Journal of medical …, 2014 - microbiologyresearch.org
Primary clarithromycin resistance is the main factor affecting the efficacy of Helicobacter
pylori therapy. This study aimed:(i) to assess the concordance between phenotypic (culture) …