Update on the genetics of spondyloarthritis–ankylosing spondylitis and psoriatic arthritis

V Chandran, P Rahman - Best Practice & Research Clinical Rheumatology, 2010 - Elsevier
Spondyloarthritis refers to a group of inflammatory rheumatic diseases that share common
clinical and genetic characteristics. Due to the rapid advances in technology and …

Advances in the genetics of spondyloarthritis and clinical implications

DD O'Rielly, P Rahman - Current rheumatology reports, 2013 - Springer
Spondyloarthritis (SpA) is a group of inflammatory rheumatic diseases whose main clinical
feature is inflammation of the axial spine. Articular, periarticular, and extra-articular …

A review of the advances in understanding the genetic basis of spondylarthritis and emerging clinical benefit

M Stadler, SS Zhao, J Bowes - Best Practice & Research Clinical …, 2024 - Elsevier
Spondyloarthropathies (SpA), including ankylosing spondylitis (AS) and psoriatic arthritis
(PsA), have been shown to have a substantial genetic predisposition based on heritability …

[HTML][HTML] Genomics of ankylosing spondylitis

GP Thomas, MA Brown - Discovery medicine, 2010 - discoverymedicine.com
Ankylosing spondylitis (AS) is the prototypic and most prevalent and debilitating
spondyloarthropathy, a group of arthritides where the spine and pelvis are specifically …

The genetics of spondyloarthritis

R Díaz-Peña, P Castro-Santos, J Durán… - Journal of Personalized …, 2020 - mdpi.com
The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases
with common features in terms of clinical presentation and genetic predisposition. SpA is …

[PDF][PDF] Genetics of ankylosing spondylitis and rheumatoid arthritis: where are we at currently, and how do they compare?

WP Maksymowych, MA Brown - Clinical & Experimental …, 2009 - clinexprheumatol.org
Both ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are common, highly heritable
conditions, the pathogenesis of which are incompletely understood. Gene-mapping studies …

Genetics and functional genomics of spondyloarthritis

F Costantino, M Breban, HJ Garchon - Frontiers in immunology, 2018 - frontiersin.org
Spondyloarthritis (SpA) is a chronic inflammatory disorder with high heritability but with
complex genetics. It encompasses several entities that share common clinical features. Most …

Progress of genome‐wide association studies of ankylosing spondylitis

Z Li, MA Brown - Clinical & translational immunology, 2017 - Wiley Online Library
Ankylosing spondylitis (AS) is an immune‐mediated arthritis which primarily affects the spine
and sacroiliac joints. Significant progress has been made in discovery of genetic …

Combined analysis of three whole genome linkage scans for Ankylosing Spondylitis

KW Carter, A Pluzhnikov, AE Timms… - …, 2007 - academic.oup.com
Objective. Ankylosing spondylitis (AS) is a debilitating chronic inflammatory condition with a
high degree of familiality (λ s= 82) and heritability (> 90%) that primarily affects spinal and …

Genetic susceptibility factors for psoriatic arthritis

M Castelino, A Barton - Current opinion in rheumatology, 2010 - journals.lww.com
Large, well powered genome-wide association studies are currently underway and should
provide further insights into the cause of this common arthritic disease over the next few …