Bats are the longest-lived mammals, given their body size. However, the underlying
molecular mechanisms of their extended healthspans are poorly understood. To address …

Comparative analyses of bats indicate that hibernation is associated with increased
longevity among species. However, it is not yet known if hibernation affects biological …

Understanding aging is a grand challenge in biology. Exceptionally long-lived animals have
mechanisms that underpin extreme longevity. Telomeres are protective nucleotide repeats …

Autophagy maintains cellular homeostasis and its dysfunction has been implicated in aging.
Bats are the longest-lived mammals for their size, but the molecular mechanisms underlying …

Bats account for one-fifth of mammalian species, are the only mammals with powered flight,
and are among the few animals that echolocate. The insect-eating Brandt's bat (Myotis …

Bats and birds live substantially longer on average than non-flying mammals of similar body
size. The combination of small body size, high metabolic rates, and long lifespan in bats and …

Background Chiroptera, the bats, are the only order of mammals capable of true self-
powered flight. Bats exhibit a number of other exceptional traits such as echolocation, viral …

Vespertilionid bats (Mammalia: Order Chiroptera) live 3–10 times longer than other
mammals of an equivalent body size. At present, nothing is known of how bat fecal …

Bats are the only mammals capable of true, powered flight, which drives an extremely high
metabolic rate. The “Free Radical Theory of Ageing”(FTRA) posits that a high metabolic rate …

A changing microbiome has been linked to biological aging in mice and humans,
suggesting a possible role of gut flora in pathogenic aging phenotypes. Many bat species …