[HTML][HTML] Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture: A population-based cohort study

J van Dalem, NCC Werkman, JP van den Bergh… - Diabetes Research and …, 2022 - Elsevier
Aims Sodium-glucose co-transporter-2 (SGLT-2) inhibitor-induced weight loss might play a
role in the debated elevated fracture risk with these agents. The aim of the current study was …

Risk of bone fracture associated with sodium–glucose cotransporter-2 inhibitor treatment: a meta-analysis of randomized controlled trials

L Cheng, YY Li, W Hu, F Bai, HR Hao, WN Yu… - Diabetes & …, 2019 - Elsevier
Aim To evaluate the association between sodium–glucose cotransporter-2 (SGLT2)
inhibitors and risk of bone fractures in patients with type 2 diabetes mellitus (T2DM) …

SGLT2 inhibitor treatment is not associated with an increased risk of osteoporotic fractures when compared to GLP-1 receptor agonists: A nationwide cohort study

ZK Al-Mashhadi, R Viggers, J Starup-Linde… - Frontiers in …, 2022 - frontiersin.org
Background Type 2 diabetes mellitus (T2D) is associated with an increased fracture risk. It is
debated whether sodium-glucose cotransporter 2 (SGLT2) inhibitors influence fracture risk …

Sodium–glucose cotransporter 2 inhibitors do not increase the risk of fractures in real‐world clinical practice in Korea: A national observational cohort study

KH Ha, DJ Kim, YJ Choi - Journal of Diabetes Investigation, 2022 - Wiley Online Library
Abstract Aims/Introduction This study aimed to determine whether sodium–glucose
cotransporter 2 inhibitors (SGLT2i) were related to increased fracture risk in adults with type …

Impact of sodium‐glucose cotransporter‐2 inhibitors on the risk of hip fracture in older patients in Japan using a nationwide administrative claims database: A matched …

T Saito, S Nojiri, T Kasai, Y Hiratsuka… - Geriatrics & …, 2023 - Wiley Online Library
Aim Some clinical trials have shown that sodium‐glucose cotransporter‐2 (SGLT2) inhibitors
are associated with fracture risk. However, this notion remains controversial. This study …

Effect of SGLT2 inhibitors on fractures, BMD, and bone metabolism markers in patients with type 2 diabetes mellitus: a systematic review and meta-analysis

X Wang, F Zhang, Y Zhang, J Zhang, Y Sheng… - Osteoporosis …, 2023 - Springer
This meta-analysis aims to evaluate the impact of Sodium Glucose Transporter 2 (SGLT2)
inhibitors on fractures, bone mineral density (BMD), and bone metabolism markers in type 2 …

Sodium‐glucose cotransporter 2 (SGLT2) inhibitors and fracture risk in patients with type 2 diabetes mellitus: a meta‐analysis

D Ruanpeng, P Ungprasert, J Sangtian… - Diabetes/metabolism …, 2017 - Wiley Online Library
Background Sodium‐glucose cotransporter 2 (SGLT2) inhibitors could potentially alter
calcium and phosphate homeostasis and may increase the risk of bone fracture. Methods …

Effects of SGLT2 inhibitors on fractures and bone mineral density in type 2 diabetes: An updated meta‐analysis

X Li, T Li, Y Cheng, Y Lu, M Xue, L Xu… - Diabetes/metabolism …, 2019 - Wiley Online Library
Background The aim of the study is to update and determine the effects of sodium glucose
cotransporter 2 (SGLT2) inhibitor therapy on fracture and bone mineral density (BMD) in …

Sodium-glucose cotransporter 2 inhibitors and fracture risk in patients with type 2 diabetes mellitus: A systematic literature review and Bayesian network meta-analysis …

M Azharuddin, M Adil, P Ghosh, M Sharma - Diabetes Research and …, 2018 - Elsevier
Aim To perform a systematic literature review and network meta-analysis (NMA) of
randomized controlled trials (RCTs) to estimate effect of SGLT2 inhibitors on fracture risk in …

Sodium‐glucose co‐transporter 2 inhibitors and the risk of fractures: A propensity score‐matched cohort study

S Adimadhyam, TA Lee, GS Calip… - … and Drug Safety, 2019 - Wiley Online Library
Purpose To determine the risk of fractures associated with sodium‐glucose co‐transporter 2
inhibitors (SGLT2i) compared with dipeptidyl peptidase‐4 inhibitors (DPP4i). Methods We …