Current Status of Radiolabeled Monoclonal Antibodies Targeting PSMA for Imaging and Therapy

M Abusalem, L Martiniova, S Soebianto, L DePalatis… - Cancers, 2023 - mdpi.com
Simple Summary The prostate-specific membrane antigen (PSMA) protein present in most
prostate cancer cells has emerged as a promising target for the imaging and treatment of …

Radiolabeled mAbs as molecular imaging and/or therapy agents targeting PSMA

D Psimadas, V Valotassiou, S Alexiou… - Cancer …, 2018 - Taylor & Francis
Molecular imaging and therapy is a rapidly evolving field in research and clinical medicine.
The use of the exciting and attractive properties of radioisotopes for imaging and therapy …

Prostate-specific membrane antigen-targeted radiopharmaceuticals in diagnosis and therapy of prostate cancer: Current status and future perspectives

M Lin, RT Ta, K Kairemo, DB Le… - Cancer Biotherapy & …, 2021 - liebertpub.com
Prostate cancer is the most common cancer to affect men in the United States and the
second most common cancer in men worldwide. Prostate-specific membrane antigen …

Recent advances in prostate-specific membrane antigen-based radiopharmaceuticals

W Diao, H Cai, L Chen, X Jin, X Liao… - Current Topics in …, 2019 - ingentaconnect.com
Background: Prostate cancer (PCa) is the most common sex-related malignancy with high
mortality in men worldwide. Prostate-specific membrane antigen (PSMA) is overexpressed …

PSMA-targeted radiopharmaceuticals for imaging and therapy

HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …

Antibodies targeting Prostate-Specific Membrane Antigen positive prostate cancer: from diagnostic imaging to theranostics

T Roumeguère, F Aoun, S Albisinni… - Current opinion in …, 2021 - journals.lww.com
PSMA targeting antibodies are very promising for further clinical investigation and continue
to be a momentous research area, for both imaging and therapeutic settings. Although some …

Prostate Specific Membrane Antigen-Based Therapeutics

ST Tagawa, JR Osborne, S Vallabhajosula… - Prostate Cancer: A …, 2013 - Springer
Prostate cancer is the most common non-cutaneous malignancy affecting men in the US,
leading to significant morbidity and mortality. While significant therapeutic advances have …

PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy of Prostate Cancer

VK Tishchenko, VM Petriev, OP Vlasova… - Physics of Atomic …, 2022 - Springer
Molecular changes in prostate cancer lead to increased expression of prostate-specific
membrane antigen (PSMA), which is a suitable target for imaging and therapy using …

Recent developments of prostate-specific membrane antigen (PSMA)-specific radiopharmaceuticals for precise imaging and therapy of prostate cancer: an overview

SM Okarvi - Clinical and Translational Imaging, 2019 - Springer
Despite significant research activities and subsequent progress made in the fight against
cancer over the last few decades, prostate cancer remains a major health-related problem …

PSMA-targeting radiopharmaceuticals for prostate cancer therapy: recent developments and future perspectives

M El Fakiri, NM Geis, N Ayada, M Eder, AC Eder - Cancers, 2021 - mdpi.com
Simple Summary One of the most frequently diagnosed cancer in men is adenocarcinoma of
the prostate. Once the disease is metastatic, only very limited treatment options are …