The molecular basis for SARS-CoV-2 binding to dog ACE2

Z Zhang, Y Zhang, K Liu, Y Li, Q Lu, Q Wang… - Nature …, 2021 - nature.com
SARS-CoV-2 can infect many domestic animals, including dogs. Herein, we show that dog
angiotensin-converting enzyme 2 (dACE2) can bind to the SARS-CoV-2 spike (S) protein …

SARS‐CoV‐2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability

V Armijos‐Jaramillo, J Yeager, C Muslin… - Evolutionary …, 2020 - Wiley Online Library
The emergence of SARS‐CoV‐2 has resulted in nearly 1,280,000 infections and 73,000
deaths globally so far. This novel virus acquired the ability to infect human cells using the …

Multidisciplinary approaches identify compounds that bind to human ACE2 or SARS-CoV-2 spike protein as candidates to block SARS-CoV-2–ACE2 receptor …

CJ Day, B Bailly, P Guillon, L Dirr, FEC Jen… - MBio, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged virus
that causes coronavirus infectious disease 2019 (COVID-19). SARS-CoV-2 spike protein …

Structural basis for human receptor recognition by SARS-CoV-2 Omicron variant BA. 1

Q Geng, K Shi, G Ye, W Zhang, H Aihara, F Li - Journal of Virology, 2022 - Am Soc Microbiol
The highly contagious and fast-spreading omicron variant of SARS-CoV-2 infects the
respiratory tracts efficiently. The receptor-binding domain (RBD) of the omicron spike protein …

Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

X Chen, R Li, Z Pan, C Qian, Y Yang, R You… - Cellular & molecular …, 2020 - nature.com
According to the World Health Organization (WHO) newly updated situation report on March
18th, 2020, the coronavirus disease 2019 (COVID-19) pandemic has confirmed 191,127 …

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types

Z Daniloski, TX Jordan, JK Ilmain, X Guo, G Bhabha… - Elife, 2021 - elifesciences.org
A novel variant of the SARS-CoV-2 virus carrying a point mutation in the Spike protein
(D614G) has recently emerged and rapidly surpassed others in prevalence. This mutation is …

[HTML][HTML] Reversal of the unique Q493R mutation increases the affinity of Omicron S1-RBD for ACE2

AM Philip, WS Ahmed, KH Biswas - Computational and Structural …, 2023 - Elsevier
Abstract The SARS-CoV-2 Omicron variant containing 15 mutations, including the unique
Q493R, in the spike protein receptor binding domain (S1-RBD) is highly infectious. While …

SARS-CoV-2: receptor and co-receptor tropism probability

N Eslami, PS Aghbash, A Shamekh… - Current …, 2022 - Springer
The recent pandemic which arose from China, is caused by a pathogenic virus named
“severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2)”. Its rapid global …

Structural analysis of receptor engagement and antigenic drift within the BA. 2 spike protein

JW Saville, D Mannar, X Zhu, AM Berezuk, S Cholak… - Cell Reports, 2023 - cell.com
The BA. 2 sub-lineage of the Omicron (B. 1.1. 529) severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variant rapidly supplanted the original BA. 1 sub-lineage in …

Vaccine-escape and fast-growing mutations in the United Kingdom, the United States, Singapore, Spain, India, and other COVID-19-devastated countries

R Wang, J Chen, K Gao, GW Wei - Genomics, 2021 - Elsevier
Abstract Recently, the SARS-CoV-2 variants from the United Kingdom (UK), South Africa,
and Brazil have received much attention for their increased infectivity, potentially high …