S100B Secretion in Acute Brain Slices: Modulation by Extracellular Levels of Ca2+ and K+

P Nardin, L Tortorelli, A Quincozes-Santos… - Neurochemical …, 2009 - Springer
Hippocampal slices have been widely used to investigate electrophysiological and
metabolic neuronal parameters, as well as parameters of astroglial activity including protein …

High glutamate decreases S100B secretion stimulated by serum deprivation in astrocytes

D Gonçalves, J Karl, M Leite, L Rotta, C Salbego… - …, 2002 - journals.lww.com
S100B is a calcium-binding protein expressed and secreted by astrocytes, playing a
neurotrophic role in neighboring cells. A protective role of the S100B against glutamate …

Astroglial S100B Secretion Is Mediated by Ca2+ Mobilization from Endoplasmic Reticulum: A Study Using Forskolin and DMSO as Secretagogues

MC Leite, F Galland, MC Guerra, L Rodrigues… - International Journal of …, 2023 - mdpi.com
S100B, a homodimeric Ca2+-binding protein, is produced and secreted by astrocytes, and
its extracellular levels have been used as a glial marker in brain damage and …

S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate

NG Selistre, L Rodrigues, BC Federhen, V Gayger-Dias… - Metabolites, 2023 - mdpi.com
S100B is a calcium-binding protein produced and secreted by astrocytes in response to
various extracellular stimuli. C6 glioma cells are a lineage commonly employed for astroglial …

High glutamate decreases S100B secretion by a mechanism dependent on the glutamate transporter

F Tramontina, MC Leite, D Gonçalves… - Neurochemical …, 2006 - Springer
Several molecules have been shown to be involved in glial-neuronal communication,
including S100B, an astrocyte-derived neurotrophic cytokine. Extracellular S100B protects …

Enhanced calcium transients in glial cells in neonatal cerebellar cultures derived from S100B null mice

Z Xiong, D O'Hanlon, LE Becker, J Roder… - Experimental cell …, 2000 - Elsevier
S100B is the major low-affinity Ca2+-binding protein in astrocytes. In order to study the role
of S100B in the maintenance of Ca2+ homeostasis, we generated S100B null mice by a …

S100B content and secretion decrease in astrocytes cultured in high-glucose medium

P Nardin, F Tramontina, MC Leite… - Neurochemistry …, 2007 - Elsevier
S100B is an astrocyte calcium-binding protein that plays a regulatory role in the cytoskeleton
and cell cycle. Moreover, extracellular S100B, a marker of glial activation in several …

β-Hydroxy-butyrate alters the extracellular content of S100B in astrocyte cultures

M Leite, JK Frizzo, P Nardin, LMV De Almeida… - Brain research …, 2004 - Elsevier
Astrocytes have a variety of roles in maintaining neural tissue physiology, including
energetic support, uptake and metabolism of glutamate and secretion of neurotrophic …

S100B in brain damage and neurodegeneration

M Rothermundt, M Peters, JHM Prehn… - … research and technique, 2003 - Wiley Online Library
S100B is a calcium‐binding peptide produced mainly by astrocytes that exert paracrine and
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …

Extracellular S100β disrupts Bergman glia morphology and synaptic transmission in cerebellar Purkinje cells

OS Belozor, DA Yakovleva, IV Potapenko, AN Shuvaev… - Brain Sciences, 2019 - mdpi.com
Astrogliosis is a pathological process that affects the density, morphology, and function of
astrocytes. It is a common feature of brain trauma, autoimmune diseases, and …