Clinical studies with intrastriatal transplants of human embryonic mesencephalic tissue have
provided proof-of-principle for the cell replacement strategy in Parkinson's disease (PD) …

In Parkinson's disease (PD), the main pathology is a loss of nigrostriatal dopamine (DA)
neurons. Clinical trials with intrastriatal transplantation of human embryonic mesencephalic …

Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …

Clinical studies involving intrastriatal transplantation of embryonic mesencephalic tissue in
patients with Parkinson disease (PD) have provided proof-of-principle for the cell …

The main pathology underlying motor symptoms in Parkinson's disease (PD) is a rather
selective degeneration of nigrostriatal dopamine (DA) neurons. Intrastriatal transplantation …

The clinical studies with intrastriatal transplants of fetal mesencephalic tissue in Parkinson's
disease (PD) patients have provided proof-of-principle for the cell replacement strategy in …

Clinical studies with intrastriatal transplants of embryonic mesencephalic tissue in patients
with Parkinson's disease (PD) provide proof-of-principle for the cell replacement strategy in …

Cell replacement therapy in Parkinson's disease (PD) has so far been based on the use of
primary dopaminergic (DA) neuroblasts obtained from the brain of aborted human fetuses …

The clinical trials with intrastriatal transplantation of human fetal mesencephalic tissue, rich
in dopaminergic neurons, in Parkinson's disease (PD) patients show that cell replacement …

Abstract Parkinson's disease (PD), one of the most frequent neurodegenerative disorders, is
primarily caused by the selective degeneration of specific neuronal populations, particularly …