Heterotopic ossification (HO), the formation of extra-skeletal bone in soft tissues, is a
pathologic process occurring after substantial burns or trauma, or in patients with type I bone …

The pathologic development of heterotopic ossification (HO) is well described in patients
with extensive trauma or with hyperactivating mutations of the bone morphogenetic protein …

Non-hereditary heterotopic ossification (NHHO) may occur after musculoskeletal trauma,
central nervous system (CNS) injury, or surgery. We previously described circulating …

Heterotopic ossification (HO), characterized by the formation of mature bone in the soft
tissues, is a complication that can accompany musculoskeletal injury, and it is a frequent …

Background Heterotopic ossification (HO), either acquired (aHO) or hereditary, such as
fibrodysplasia ossificans progressiva (FOP), is a serious condition without effective …

Heterotopic ossification (HO) is a form of pathological cell-fate change of mesenchymal
stem/precursor cells (MSCs) that occurs following traumatic injury, limiting range of motion in …

Trauma-induced heterotopic ossification (HO) occurs after severe musculoskeletal injuries
and burns, and presents a significant barrier to patient rehabilitation. Interestingly, the …

Heterotopic ossification (HO) is a common and debilitating complication of burns, traumatic
brain injuries, and musculoskeletal trauma and surgery. Although the exact mechanism of …

Heterotopic ossification (HO) is a pathological process resulting in aberrant bone formation
and often involves synovial lined tissues. During this process, mesenchymal progenitor cells …

Put most simply, heterotopic ossification (HO) is the abnormal formation of bone at
extraskeletal sites. HO can be classified into two main subtypes, genetic and acquired …