Expression of membrane-type (MT) 5 matrix metalloproteinase (MMP) in the mouse brain
was examined. MT5-MMP was expressed in the cerebrum in embryos, but it declined after …

An intricate balance between extracellular matrix (ECM) synthesis and degradation must be
maintained during developmental tissue remodeling. Matrix metalloproteinases (MMPs) are …

The matrix metalloproteinase (MMP) family, comprising more than 20 isoforms, modulates
the extracellular milieu by degrading extracellular matrix (ECM) proteins. Because MMP is …

Membrane-type 3 matrix metalloproteinase (MT3-MMP) is a novel MT-MMP which has a
transmembrane domain at the C terminus, and mediates activation of pro-gelatinase A, just …

Matrix metalloproteinases (MMPs) have been proposed to remodel the extracellular
environment of neurons. Here, we report that the metalloproteinase membrane-type 5 MMP …

Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are essential for coordinated
extracellular matrix turnover during central nervous system development. Reverse …

We have recently identified the fifth member of the membrane‐type matrix metalloproteinase
subfamily, MT5‐MMP/MMP24, which is expressed in a brain specific manner (Duanqing Pei …

The matrix metalloproteinases (MMPs) are implicated in several activities within the nervous
system. Although many functions of abnormally elevated MMPs are undesirable, the discrete …

A new member of the membrane-type matrix metalloproteinase (MT-MMP) subfamily
tentatively named MT5-MMP was isolated from mouse brain cDNA library. It is predicted to …

Matrix metalloproteinases (MMPs) degrade the extracellular matrix and are implicated in the
pathogenesis of several neurological diseases. Secreted in proforms, the MMPs require …