By using the Ca 2+-sensitive indictor Fura-2/AM, the cytosolic Ca 2+ levels [Ca 2+] i were
measured in type 1 astrocytes in rat cortical astroglial primary cultures, after stimulation with …

The properties of GABA receptor-mediated responses were examined in noncultured
astrocytes, acutely isolated from the mature rat hippocampus. Whole-cell patch clamping …

Studies over the last decade provided evidence that in a dynamic interaction with neurons
glial cell astrocytes contribut to fundamental phenomena in the brain. Most of the knowledge …

Baclofen, a GABA B receptor agonist, and GABA attenuated by 60% the high K+-evoked 45
Ca 2+ uptake into cultured cerebellar granule cells with an EC 50 of 110±18 nM and 2.4±0.2 …

We have previously demonstrated that human astrocytes are GABAergic cells. Throughout
the adult human brain, they express the GABA synthesizing enzyme GAD 67, the GABA …

1. Changes in intracellular Ca2+ concentration ([Ca2+] i) induced by activation of GABAA
receptors (synaptic stimulation or application of the GABAA agonist isoguvacine) were …

The development of oligodendrocytes from their precursor cells can be studied in vitro by
using a culture system in which cells can be identified at different developmental stages. We …

Abstract γ‐Aminobutyric acid (GABA) B receptor‐mediated modulation of spontaneous
GABA release onto Purkinje cells was investigated in cerebellar slices from 3‐to 5‐week‐old …

Synaptic activation of GABAA receptors induces neuronal uptake of Ca2+ in adult rat
hippocampal slices. Synaptically evoked transmembrane movements of Ca2+ in the adult …

GABA receptors are distributed widely throughout the central nervous system on a variety of
cell types. It has become increasingly clear that astrocytes, both in cell culture and tissue …