All people are unique and so are their diseases. Our genomes, disease histories, behavior,
and lifestyles are all different; therefore it is not too surprising that people often respond …

We are unique and so are our diseases. Our genomes, disease histories, behavior, and
lifestyles are all different. It is not too surprising, therefore, that we often respond differently to …

In our recent paper [1], we describe a biologydriven approach to translate cancer genomic
data into clinically actionable information for personalized patient therapy selection. Despite …

Abstract Treatment outcomes in oncology are determined by complex interactions among
treatment, anatomical, and patient-related variables. A key component of oncology research …

Every tumour is different. They arise in patients with different genomes, from cells with
different epigenetic modifications, and by random processes affecting the genome and/or …

Cancer is a leading cause of death worldwide, claiming millions of lives each year. Cancer
biology is an essential research field to understand how cancer develops, evolves, and …

Background In recent years, the availability of high throughput technologies, establishment
of large molecular patient data repositories, and advancement in computing power and …

Cancer has been a perennial challenge to clinicians and researchers for more than a
century. The existing treatment modalities are" effective" only in the subsets of patient …

The traditional bench-to-bedside pipeline involves using model systems and patient
samples to provide insights into pathways deregulated in cancer. This discovery reveals …

Cancer is a highly heterogeneous disease with complex underlying biology. For these
reasons, effective cancer treatment is still a challenge. Nowadays, it is clear that a cancer …