TRPM8 (melastatine-related transient receptor potential member 8), a member of the
transient receptor potential (TRP) superfamily of cation channels, has been shown to be a …

Overexpression of the cation-permeable channel TRPM8 in prostate cancers might
represent a novel opportunity for their treatment. Inhibitors of TRPM8 reduce the growth of …

During the past 5 years it has emerged that the transient receptor potential (TRP) family of
Ca 2+-and Na+-permeable channels plays a diverse and important role in cell biology and …

The transient receptor potential ion channel of the melastatin subfamily, TRPM8, is a major
cold receptor in the peripheral nervous system. Along with the sensory neurons, the TRPM8 …

The Ca2+-permeable channel TRPM8 is thought to play an important role in the
pathophysiology of prostate cancer. We have investigated the intracellular location of …

Metastatic prostate cancer (mPCa) is one of the leading causes of cancer-related mortality in
both the US and Europe. Androgen deprivation is the first-line therapy for mPCa; however …

The cold and menthol receptor TRPM8 is highly expressed in prostate and prostate cancer
(PC). Recently, we identified that TRPM8 is as an ionotropic testosterone receptor. The …

We have identified a novel function for a member of the transient receptor potential (TRP)
protein super-family, TRPM2, in prostate cancer cell proliferation. TRPM2 encodes a non …

In prostate carcinogenesis, androgens are known to control the expression of the transient
receptor potential melastatin 8 (TRPM8) protein via activation of androgen receptor (AR) …

In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has
emerged as a promising prognostic marker and putative therapeutic target in prostate …