[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies
Immediately from the outset of the COVID-19 pandemic, researchers from diverse
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
[HTML][HTML] Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies
C Yi, X Sun, J Ye, L Ding, M Liu, Z Yang, X Lu… - Cellular & molecular …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus
SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein …
SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein …
[HTML][HTML] Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain
X Chi, X Liu, C Wang, X Zhang, X Li, J Hou… - Nature …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads worldwide and
leads to an unprecedented medical burden and lives lost. Neutralizing antibodies provide …
leads to an unprecedented medical burden and lives lost. Neutralizing antibodies provide …
[HTML][HTML] Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry
Understanding the mechanism for antibody neutralization of SARS-CoV-2 is critical for the
development of effective therapeutics and vaccines. We recently isolated a large number of …
development of effective therapeutics and vaccines. We recently isolated a large number of …
[HTML][HTML] A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
Vaccines and therapeutics are urgently needed for the pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …
[HTML][HTML] A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
T Noy-Porat, E Makdasi, R Alcalay, A Mechaly… - Nature …, 2020 - nature.com
The novel highly transmissible human coronavirus SARS-CoV-2 is the causative agent of
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …
the COVID-19 pandemic. Thus far, there is no approved therapeutic drug specifically …
[PDF][PDF] Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B. 1.1. 7 variant
C Graham, J Seow, I Huettner, H Khan, N Kouphou… - Immunity, 2021 - cell.com
Interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the receptor ACE2
on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
Competitive SARS-CoV-2 serology reveals most antibodies targeting the spike receptor-binding domain compete for ACE2 binding
JR Byrnes, XX Zhou, I Lui, SK Elledge, JE Glasgow… - MSphere, 2020 - Am Soc Microbiol
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread
around the world, there is an urgent need for new assay formats to characterize the humoral …
around the world, there is an urgent need for new assay formats to characterize the humoral …
The SARS-CoV-2 receptor-binding domain elicits a potent neutralizing response without antibody-dependent enhancement
SUMMARY The SARS-coronavirus 2 (SARS-CoV-2) spike (S) protein mediates entry of
SARS-CoV-2 into cells expressing the angiotensin-converting enzyme 2 (ACE2). The S …
SARS-CoV-2 into cells expressing the angiotensin-converting enzyme 2 (ACE2). The S …
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Z Lv, YQ Deng, Q Ye, L Cao, CY Sun, C Fan, W Huang… - Science, 2020 - science.org
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health …
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health …