Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract. Cytokine-targeted therapies have transformed the treatment of IBD, providing control of …

Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are
characterized by uncontrolled activation of intestinal immune cells in a genetically …

Abstract Inflammatory Bowel Diseases (IBD), namely Crohn's Disease and Ulcerative Colitis,
cause a significant disease burden in modern civilization. Ever since the introduction of anti …

Cytokines have a crucial role in the pathogenesis of inflammatory bowel diseases (IBDs),
such as Crohn's disease and ulcerative colitis, where they control multiple aspects of the …

Pathogenesis of the inflammatory bowel diseases (IBDs), such as ulcerative colitis (UC) and
Crohn's disease (CD), involve proinflammatory changes within the microbiota, chronic …

Inflammatory bowel diseases (IBDs) are complex and chronic disabling conditions resulting
from a dysregulated dialogue between intestinal microbiota and components of both the …

Introduction: Although the etiology of inflammatory bowel diseases (IBD) remains unknown,
accumulating evidence suggests that the intestinal tissue damage in these disorders is due …

The current understanding of inflammatory bowel disease (IBD) pathogenesis implicates a
complex interaction between host genetics, host immunity, microbiome, and environmental …

Introduction: Cytokines represent the key pathophysiologic elements that govern the
initiation, progression, and, in some circumstances, the resolution of the inflammation …

Current inflammatory bowel disease (IBD) therapies are ineffective in a high proportion of
patients. Combining bulk and single-cell transcriptomics, quantitative histopathology and in …