G protein-coupled receptors (GPCRs) are privileged structural scaffolds in biology that have
the versatility to regulate diverse physiological processes. Interestingly, many GPCR ligands …

Recent solved structures of G protein-coupled receptors (GPCRs) provide insights into
variation of the structure and molecular mechanisms of GPCR activation. In this review, we …

G protein-coupled receptors (GPCRs) are critical regulators of human physiology and make
up the largest single class of therapeutic drug targets. Although GPCRs regulate highly …

The discovery of biased signaling at G protein-coupled receptors (GPCRs), the largest class
of cell surface receptors and primary drug targets for numerous human diseases, has …

During the past few years, crystallography of G protein–coupled receptors (GPCRs) has
experienced exponential growth, resulting in the determination of the structures of 16 distinct …

G protein–coupled receptors (GPCRs) are versatile molecular machines that regulate the
majority of physiological responses to chemically diverse hormones and neurotransmitters …

G protein–coupled receptors (GPCRs) represent the largest family of cell membrane
proteins, with> 800 GPCRs in humans alone, and recognize highly diverse ligands, ranging …

G-protein-coupled receptors (GPCRs) are physiologically important membrane proteins that
sense signalling molecules such as hormones and neurotransmitters, and are the targets of …

G protein-coupled receptors (GPCRs) constitute the largest and the most physiologically
important membrane protein family that recognizes a variety of environmental stimuli, and …

G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …