Background—Current guidelines recommend statins in the primary prevention of
cardiovascular disease on the basis of predicted cardiovascular risk without directly …

Importance A 10-year benefit-based approach to statin therapy in primary prevention
includes younger individuals with higher low-density lipoprotein cholesterol (LDL-C) and …

Importance There are important differences among guideline recommendations for using
statin therapy in primary prevention. New recommendations from the US Preventive …

Importance Cardiovascular disease (CVD), the leading cause of mortality and morbidity in
the United States, may be potentially preventable with statin therapy. Objective To …

Importance A 2016 review for the US Preventive Services Task Force (USPSTF) found use
of statins for primary prevention of cardiovascular disease (CVD) was associated with …

Background: Cholesterol guidelines typically prioritize primary prevention statin therapy on
the basis of 10-year risk of cardiovascular disease. The advent of generic pricing may justify …

Many voices in the public and the medical community argue strongly against the widespread
use of statins for the primary prevention of atherosclerotic cardiovascular disease. Critics …

Importance Statins are a cornerstone medication in cardiovascular disease prevention, but
their use in clinical practice remains suboptimal, with less than half of people who are …

This issue of JAMA contains the latest US Preventive Services Task Force (USPSTF)
recommendation statement on statins for prevention of cardiovascular disease in adults, 1 …

Abstract Background and Aims Statin recommendations in primary prevention depend upon
risk algorithms. Moreover, with intermediate risk, risk enhancers and de-enhancers are …