Thyroid cancer is associated with a broad range of different mutations, including RET
(rearranged during transfection) fusion genes. The importance of characterizing RET fusion …

Background RET rearrangements have emerged as a new actionable alteration in papillary
thyroid cancers (PTC). These fusions may involve many partner genes, are thought to be …

Introduction: Although it is a rare malignancy in the pediatric population, thyroid cancer, at
this stage of life, is associated with advanced stages of the disease when compared to …

Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with
increasing incidence. Pediatric PTCs have distinct clinical and pathological features and …

BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma
(PTC), has been recently reported in children. METHODS The histopathology of 28 …

Background In the field of gene fusions driving tumorigenesis in papillary thyroid carcinoma
(PTC), rearrangement of the proto-oncogene RET is the most frequent alteration. Apart from …

To recommend a reliable and clinically realistic RET/PTC rearrangement detection assay for
papillary thyroid carcinoma (PTC), we compared multiplex quantitative polymerase chain …

Thyroid carcinomas exhibit various genetic alterations, including the RET and NTRK fusion
genes that are targets for molecular therapies. Thus, detecting fusion genes is crucial for …

Background Rearranged during transfection (RET) is a well-known proto-oncogene. Multiple
RET oncogenic alterations have been identified, including fusions and mutations. Although …

Background Rearrangements of RET are drivers of oncogenesis, traceable in different
cancer types as papillary thyroid carcinoma (PTC), non-small cell lung cancer, colorectal or …