Intermediate versus standard-dose prophylactic anticoagulation and statin therapy versus placebo in critically-ill patients with COVID-19: Rationale and design of the …

B Bikdeli, AH Talasaz, F Rashidi, B Sharif-Kashani… - Thrombosis research, 2020 - Elsevier
Background Microvascular and macrovascular thrombotic events are among the hallmarks
of coronavirus disease 2019 (COVID-19). Furthermore, the exuberant immune response is …

Effect of intermediate-dose vs standard-dose prophylactic anticoagulation on thrombotic events, extracorporeal membrane oxygenation treatment, or mortality among …

S Mazloomzadeh, S Khaleghparast, B Ghadrdoost… - Jama, 2021 - jamanetwork.com
Importance Thrombotic events are commonly reported in critically ill patients with COVID-19.
Limited data exist to guide the intensity of antithrombotic prophylaxis. Objective To evaluate …

American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: May 2021 update on the use of …

A Cuker, EK Tseng, R Nieuwlaat… - Blood …, 2021 - ashpublications.org
Abstract Background: COVID-19–related critical illness is associated with an increased risk
of venous thromboembolism (VTE). Objective: These evidence-based guidelines of the …

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week

ME Farkouh, GW Stone, A Lala, E Bagiella… - Journal of the American …, 2022 - jacc.org
Clinical, laboratory, and autopsy findings support an association between coronavirus
disease-2019 (COVID-19) and thromboembolic disease. Acute COVID-19 infection is …

Anticoagulation and antiplatelet therapy for prevention of venous and arterial thrombotic events in critically ill patients with COVID-19: COVID-PACT

EA Bohula, DD Berg, MS Lopes, JM Connors, I Babar… - Circulation, 2022 - Am Heart Assoc
Background: The efficacy and safety of prophylactic full-dose anticoagulation and
antiplatelet therapy in critically ill COVID-19 patients remain uncertain. Methods: COVID …

Intermediate-dose versus standard-dose prophylactic anticoagulation in patients with COVID-19 admitted to the intensive care unit: 90-day results from the …

B Bikdeli, AH Talasaz, F Rashidi… - Thrombosis and …, 2022 - thieme-connect.com
Background Thrombotic complications are considered among the main extrapulmonary
manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration of …

[HTML][HTML] Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID‐19: a multi‐center, open‐label, randomized controlled trial

US Perepu, I Chambers, A Wahab, P Ten Eyck… - Journal of Thrombosis …, 2021 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID‐19) is associated with
coagulopathy but the optimal prophylactic anticoagulation therapy remains uncertain and …

[HTML][HTML] Good practice statements for antithrombotic therapy in the management of COVID‐19: guidance from the SSC of the ISTH

AC Spyropoulos, JM Connors, JD Douketis… - Journal of Thrombosis …, 2022 - Elsevier
Despite the emergence of high quality randomized trial data with the use of antithrombotic
agents to reduce the risk of thromboembolism, end‐organ failure, and possibly mortality in …

[HTML][HTML] The current status of thrombosis and anticoagulation therapy in patients with COVID-19 in Japan: From the CLOT-COVID study

Y Nishimoto, S Yachi, M Takeyama, I Tsujino… - Journal of …, 2022 - Elsevier
Background Data on thrombosis and current real-world management strategies for
anticoagulation therapy are scarce but important for understanding current issues and …

Intermediate-to-therapeutic versus prophylactic anticoagulation for coagulopathy in hospitalized COVID-19 patients: a systemic review and meta-analysis

S Zhang, Y Li, G Liu, B Su - Thrombosis Journal, 2021 - Springer
Background Anticoagulation in hospitalized COVID-19 patients has been associated with
survival benefit; however, the optimal anticoagulant strategy has not yet been defined. The …