N-(2-Hydroxypropyl) methacrylamide (HPMA) copolymer–docetaxel–RGDfK conjugate was
synthesized, characterized, and evaluated in vitro and in vivo in comparison with untargeted …

Biodistribution, pharmacokinetics, and efficacy of prostate‐cancer‐targeted HPMA
copolymer/DTX conjugates are evaluated in nude mice bearing prostate cancer C4‐2 …

Combination of targeted delivery and controlled release is a powerful technique for cancer
treatment. In this paper, we describe the design, synthesis, structure validation and …

Combination therapies have been investigated to address the current challenges of anti-
cancer therapeutics. In particular, a novel paradigm of combination therapy targeting both …

N-(2-Hydroxypropyl) methacrylamide (HPMA) copolymer-RGD (Arg-Gly-Asp) conjugates
targeting the αvβ3 integrin present on angiogenic blood vessels and some tumor types have …

In this paper we describe the synthesis, physicochemical characteristics and data on the
biological activity of polymer prodrugs based on the anticancer drugs paclitaxel (PTX) and …

Purpose This study focuses on the synthesis and characterization of N-(2-hydroxypropyl)
methacrylamide (HPMA) copolymer–cyclo-RGD (Arg-Gly-Asp) conjugates for delivery of …

Tumor progression is dependent on neoangiogenesis for blood supply. Neovasculature
over-express αvβ3 integrins which recognize the Arg-Gly-Asp (RGD) sequence in the …

This review describes the design and development of N-(2-hydroxypropyl)-methacrylamide
(HPMA) copolymer–cyclic RGD conjugates for targeting tumor angiogenesis. Relative to non …

Targeted drug delivery for cancer therapy is an emerging area of research. Cancer cells
overexpress certain biomarkers that can be exploited for their targeted therapy. Cyclic cell …