An evidence that SARS-Cov-2/COVID-19 spike protein (SP) damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome …
M Kucia, J Ratajczak, K Bujko, M Adamiak… - Leukemia, 2021 - nature.com
Mounting evidence accumulates that hematopoietic stem/progenitor cells (HSPCs) and
endothelial progenitor cells (EPCs) are damaged during severe SARS-Cov-2/COVID-19 …
endothelial progenitor cells (EPCs) are damaged during severe SARS-Cov-2/COVID-19 …
COVID-19, renin-angiotensin system and endothelial dysfunction
R Amraei, N Rahimi - Cells, 2020 - mdpi.com
The newly emergent novel coronavirus disease 2019 (COVID-19) outbreak, which is caused
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
SARS-CoV-2 Spike protein promotes hyper-inflammatory response that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP …
SARS-CoV-2 infection causes an inflammatory cytokine storm and acute lung injury.
Currently there are no effective antiviral and/or anti-inflammatory therapies. Here we …
Currently there are no effective antiviral and/or anti-inflammatory therapies. Here we …
Endothelial barrier integrity in COVID-19-dependent hyperinflammation: does the protective facet of platelet function matter?
M Smeda, S Chlopicki - Cardiovascular research, 2020 - academic.oup.com
The characteristic feature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) infection (COVID-19 disease) is that its course is asymptomatic or mild in the majority of …
2) infection (COVID-19 disease) is that its course is asymptomatic or mild in the majority of …
Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation
Numerous reports of vascular events after an initial recovery from COVID-19 form our
impetus to investigate the impact of COVID-19 on vascular health of recovered patients. We …
impetus to investigate the impact of COVID-19 on vascular health of recovered patients. We …
Does eNOS derived nitric oxide protect the young from severe COVID-19 complications?
The COVID-19 pandemic poses an imminent threat to humanity, especially to the elderly.
The molecular mechanisms underpinning the age-dependent disparity for disease …
The molecular mechanisms underpinning the age-dependent disparity for disease …
COVID‐19 is an emergent disease of aging
COVID‐19 is an ongoing pandemic caused by the SARS‐CoV‐2 coronavirus that poses one
of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …
of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …
Cellular and molecular biomarkers of long COVID: a scoping review
Summary Background Long-COVID (LC) encompasses diverse symptoms lasting months
after the initial SARS-CoV-2 infection. Symptoms can be debilitating and affect the quality of …
after the initial SARS-CoV-2 infection. Symptoms can be debilitating and affect the quality of …
The SARS-CoV-2 spike protein binds and modulates estrogen receptors
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein binds
angiotensin-converting enzyme 2 as its primary infection mechanism. Interactions between …
angiotensin-converting enzyme 2 as its primary infection mechanism. Interactions between …
Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach
DLM Fonseca, IS Filgueiras, AHC Marques, E Vojdani… - npj Aging, 2023 - nature.com
Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to
immunosenescence and certain age-dependent medical conditions (eg, obesity …
immunosenescence and certain age-dependent medical conditions (eg, obesity …