Preservation of native aortic valve flow and full hemodynamic support with the TORVAD using a computational model of the cardiovascular system

JR Gohean, MJ George, KW Chang, ER Larson… - ASAIO …, 2015 - journals.lww.com
This article describes the stroke volume selection and operational design for the toroidal
ventricular assist device (TORVAD), a synchronous, positive-displacement ventricular assist …

[HTML][HTML] Reinventing the displacement left ventricular assist device in the continuous-flow era: TORVAD, the first toroidal-flow left ventricular assist device

CR Bartoli, JR Gohean, RW Smalling - Annals of cardiothoracic …, 2021 - ncbi.nlm.nih.gov
Over the past two decades, left ventricular assist device (LVAD) support has emerged as
standard therapy for adult patients with advanced, life-threatening heart failure …

Biomechanics of the aortic valve in the continuous flow VAD-assisted heart

K May-Newman, L Enriquez-Almaguer… - Asaio …, 2010 - journals.lww.com
The biomechanics of the aortic valve are altered in patients with ventricular assist devices
(VADs). During high VAD flow and low cardiac function, transvalvular pressure is high, and …

The effect of aortic valve incompetence on the hemodynamics of a continuous flow ventricular assist device in a mock circulation

MAZ Garcia, LA Enriquez, W Dembitsky… - ASAIO …, 2008 - journals.lww.com
There is evidence that the incidence of aortic valve incompetence (AI) and other valvular
pathologies may increase as more patients are submitted to longer periods of ventricular …

Characterization and development of universal ventricular assist device: computational fluid dynamics analysis of advanced design

MS Goodin, MS Showalter, DJ Horvath, BD Kuban… - ASAIO …, 2022 - journals.lww.com
We are developing a universal, advanced ventricular assist device (AVAD) with automatic
pressure regulation suitable for both left and right ventricular support. The primary goal of …

A novel toroidal-flow left ventricular assist device minimizes blood trauma: implications of improved ventricular assist device hemocompatibility

CR Bartoli, S Hennessy-Strahs, J Gohean… - The Annals of thoracic …, 2019 - Elsevier
Background Continuous-flow left ventricular assist devices (LVADs) cause blood trauma that
includes von Willebrand factor degradation, platelet activation, and subclinical hemolysis …

Fusion of aortic valve commissures in patients supported by a continuous axial flow left ventricular assist device

JO Mudd, JD Cuda, M Halushka, KA Soderlund… - The Journal of heart and …, 2008 - Elsevier
BACKGROUND: Left ventricular assist devices (LVADs) are an important therapy for
selected individuals with advanced heart failure unable to wait for a suitable donor for …

Numerical comparison of hemodynamics with atrium to aorta and ventricular apex to aorta VAD support

T Korakianitis, Y Shi - ASAIO Journal, 2007 - journals.lww.com
We report the first attempt to study with numerical methods ventricular assist device (VAD)
models and the effects of various inlet VAD cannulations, coupling physical explanations …

A mock circulatory system to assess the performance of continuous-flow left ventricular assist devices (LVADs): does axial flow unload better than centrifugal LVAD?

T Sénage, D Février, M Michel, E Pichot, D Duveau… - ASAIO …, 2014 - journals.lww.com
Hemodynamic performances comparisons between different types of left ventricular assist
devices (LVADs) remain difficult in a clinical context. The aim of this study was to create an …

[HTML][HTML] An advanced universal circulatory assist device for left and right ventricular support: First report of an acute in vivo implant

T Miyamoto, Y Kado, DJ Horvath, BD Kuban, S Sale… - JTCVS open, 2020 - Elsevier
Abstract Background The Advanced ventricular assist device (Advanced VAD) is designed
as a universal pump intended to prevent backflow in the event of pump stoppage, to …