Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Results from the ApoCOVID study

S Tanaka, C De Tymowski, M Assadi, N Zappella… - PloS one, 2020 - journals.plos.org
Introduction Severe acute respiratory syndrome coronavirus2 has caused a global
pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs) …

Cholesterol Metabolism—Impacts on SARS-CoV-2 Infection Prognosis, Entry, and Antiviral Therapies

C Wei, L Wan, Y Zhang, C Fan, Q Yan, X Yang, J Gong… - MedRxiv, 2020 - medrxiv.org
The recently emerged pathogenic SARS-coronavirus 2 (SARS-CoV-2) has spread rapidly,
leading to a global pandemic. In this study, we show that SARS-CoV-2 infection was …

Association of triglyceride/high-density lipoprotein cholesterol ratio with severe complications of COVID-19

Y Chang, J Jeon, TJ Song, J Kim - Heliyon, 2023 - cell.com
Background The coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus
can lead to serious complications such as respiratory failure, requiring mechanical …

Strong relationship between cholesterol, low-density lipoprotein receptor, Na+/H+ exchanger, and SARS-COV-2: this association may be the cause of death in the …

E Cure, M Cumhur Cure - Lipids in Health and Disease, 2021 - Springer
Lipids have a wide variety and vital functions. Lipids play roles in energy metabolism,
intracellular and extracellular signal traffic, and transport of fat-soluble vitamins. Also, they …

Decreased low-density lipoprotein cholesterol level indicates poor prognosis of severe and critical COVID-19 patients: a retrospective, single-center study

M Zhao, Z Luo, H He, B Shen, J Liang, J Zhang… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has become a global public health crisis. Reduced
low-density lipoprotein cholesterol (LDL-C) levels were observed in COVID-19 patients. The …

Lipid profile features and their associations with disease severity and mortality in patients with COVID-19

JT Sun, Z Chen, P Nie, H Ge, L Shen, F Yang… - Frontiers in …, 2020 - frontiersin.org
Background: Emerging studies have described and analyzed epidemiological, clinical,
laboratory, and radiological features of COVID-19 patients. Yet, scarce information is …

The current status of research on high-density lipoproteins (HDL): a paradigm shift from HDL quantity to HDL quality and HDL functionality

KH Cho - International journal of molecular sciences, 2022 - mdpi.com
The quantity of high-density lipoproteins (HDL) is represented as the serum HDL-C
concentration (mg/dL), while the HDL quality manifests as the diverse features of protein and …

First recombinant high-density lipoprotein particles administration in a severe ICU COVID-19 patient, a multi-omics exploratory investigation

S Tanaka, F Begue, B Veeren, A Tran-Dinh, T Robert… - Biomedicines, 2022 - mdpi.com
High-density lipoproteins (HDLs) have multiple endothelioprotective properties. During
SARS-CoV-2 infection, HDL-cholesterol (HDL-C) concentration is markedly reduced, and …

Low HDL and high triglycerides predict COVID-19 severity

L Masana, E Correig, D Ibarretxe, E Anoro, JA Arroyo… - Scientific reports, 2021 - nature.com
Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of
plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to …

Association of lipid levels with COVID-19 infection, disease severity and mortality: a systematic review and meta-analysis

V Chidambaram, H Shanmugavel Geetha… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) ranges from asymptomatic infection to
severe illness. Cholesterol in the host cell plasma membrane plays an important role in the …