Dexamethasone for severe COVID-19: how does it work at cellular and molecular levels?

T Kino, I Burd, JH Segars - International journal of molecular sciences, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) caused by infection of the severe respiratory
syndrome coronavirus-2 (SARS-CoV-2) significantly impacted human society. Recently, the …

Corticosteroids: A boon or bane for COVID-19 patients?

S Sen, B Singh, G Biswas - Steroids, 2022 - Elsevier
Several drugs and antibodies have been repurposed to treat COVID-19. Since the outcome
of the drugs and antibodies clinical studies have been mostly inconclusive or with lesser …

Corticosteroids for COVID-19: worth it or not?

F Akter, Y Araf, MJ Hosen - Molecular Biology Reports, 2022 - Springer
Pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced
COVID-19 implied the presence of excessive proinflammatory cytokines and chemokines in …

Nonsteroidal anti-inflammatory drugs and glucocorticoids in COVID-19

E Ricciotti, K Laudanski, GA FitzGerald - Advances in Biological Regulation, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is characterized by a wide spectrum of symptom …

[HTML][HTML] The Role of Glucocorticoids in the Management of COVID-19

VI Alexaki, H Henneicke - Hormone and Metabolic Research, 2021 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), caused by an infection with the novel coronavirus
SARS-CoV-2, has resulted in a global pandemic and poses an emergency to public health …

Corticosteroids in COVID-19: pros and cons

A Bahsoun, Y Fakih, R Zareef, F Bitar, M Arabi - Frontiers in Medicine, 2023 - frontiersin.org
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

Dexamethasone for the treatment of coronavirus disease (COVID-19): a review

MH Ahmed, A Hassan - SN comprehensive clinical medicine, 2020 - Springer
Abstract The World Health Organization (WHO) declared COVID-19 (novel coronavirus) as a
global pandemic in the middle of March 2020, after the disease spread to more than 150 …

Dexamethasone: Therapeutic potential, risks, and future projection during COVID-19 pandemic

S Noreen, I Maqbool, A Madni - European journal of pharmacology, 2021 - Elsevier
The current outbreak of novel COVID-19 challenges the development of an efficient
treatment plan as soon as possible. Several promising treatment options stand out as …

Role of dexamethasone and methylprednisolone corticosteroids in coronavirus disease 2019 hospitalized patients: a review

J Mehta, R Rolta, BB Mehta, N Kaushik… - Frontiers in …, 2022 - frontiersin.org
The WHO announced coronavirus disease 2019 (COVID-19) as a pandemic disease
globally on March 11, 2020, after it emerged in China. The emergence of COVID-19 has …

Inferring molecular mechanisms of dexamethasone therapy in severe COVID-19 from existing transcriptomic data

A Sharma - Gene, 2021 - Elsevier
Dexamethasone, a synthetic glucocorticoid, has previously shown mortality benefit in severe
coronavirus disease 2019 (COVID-19) in a randomized controlled trial. As the illness is …