Therapeutics for COVID-19: from computation to practices—where we are, where we are heading to

PK Ojha, S Kar, JG Krishna, K Roy, J Leszczynski - Molecular Diversity, 2021 - Springer
Abstract After the 1918 Spanish Flu pandemic caused by the H1N1 virus, the recent
coronavirus disease 2019 (COVID-19) brought us to the time of serious global health …

A critical overview of computational approaches employed for COVID-19 drug discovery

EN Muratov, R Amaro, CH Andrade, N Brown… - Chemical Society …, 2021 - pubs.rsc.org
COVID-19 has resulted in huge numbers of infections and deaths worldwide and brought
the most severe disruptions to societies and economies since the Great Depression …

Primed for global coronavirus pandemic: Emerging research and clinical outcome

S Ahamad, S Branch, S Harrelson, MK Hussain… - European journal of …, 2021 - Elsevier
The global effort to combat and contain the coronavirus disease 2019 (COVID-19) caused
by the recently discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Advances in the computational landscape for repurposed drugs against COVID-19

I Aronskyy, Y Masoudi-Sobhanzadeh, A Cappuccio… - Drug Discovery …, 2021 - Elsevier
The COVID-19 pandemic has caused millions of deaths and massive societal distress
worldwide. Therapeutic solutions are urgently needed, but de novo drug development …

Computational methods directed towards drug repurposing for COVID-19: advantages and limitations

PP Sharma, M Bansal, A Sethi, L Pena, VK Goel… - RSC …, 2021 - pubs.rsc.org
Novel coronavirus disease 2019 (COVID-19) has significantly altered the socio-economic
status of countries. Although vaccines are now available against the severe acute …

[HTML][HTML] Drug repurposing for prevention and treatment of COVID-19: a clinical landscape

MS Hossain, I Hami, MSS Sawrav, MF Rabbi, O Saha… - Discoveries, 2020 - ncbi.nlm.nih.gov
Abstract SARS-CoV-2, the novel coronavirus strain responsible for the current pandemic of
COVID-19, has rendered the entire humanity suffering. Several months have passed since …

Combating the pandemic COVID-19: clinical trials, therapies and perspectives

S Kotta, HM Aldawsari, SM Badr-Eldin… - Frontiers in molecular …, 2020 - frontiersin.org
The coronavirus disease-19 (COVID-19) is caused due to the infection by a unique single
stranded enveloped RNA virus, severe acute respiratory syndrome coronavirus-2 (SARS …

Treatments for COVID-19: Lessons from 2020 and new therapeutic options

F Salasc, T Lahlali, E Laurent, M Rosa-Calatrava… - Current Opinion in …, 2022 - Elsevier
To face the COVID-19 pandemic, prophylactic vaccines have been developed in record
time, but vaccine coverage is still limited, accessibility is not equitable worldwide, and the …

[HTML][HTML] Boosting the arsenal against COVID-19 through computational drug repurposing

G Ciliberto, L Cardone - Drug discovery today, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) world health emergency is calling scientists for
unprecedented, huge investigation efforts to urgently answer key questions: what is the …

Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements

A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
The present pandemic of SARS-CoV-2 has been a tough task for the whole world to deal
with. With the absence of specific drugs or vaccines against SARS-CoV-2, the situation is …