The neuroendocrinology of stress: the stress-related continuum of chronic disease development

A Agorastos, GP Chrousos - Molecular Psychiatry, 2022 - nature.com
Stress is defined as a state of threatened homeodynamic balance by a wide range of
intrinsic or extrinsic, real or perceived challenges or stimuli, defined as stressors. To …

Early-life stress: from neuroendocrine mechanisms to stress-related disorders

P Pervanidou, GP Chrousos - Hormone research in paediatrics, 2018 - karger.com
Stress exposure is highly prevalent in the general population; however, the experience of
stress during vulnerable periods of development has substantial and permanent effects on …

[PDF][PDF] The neurobiology of stress management

T Esch, GB Stefano - Neuroendocrinology letters, 2010 - nel.edu
Abstract BACKGROUND AND OBJECTIVE: Stress is natural and belongs to life itself. To
sustain it and even grow with it biology invented different mechanisms, since stress …

[PDF][PDF] Neuroendocrinology and pathophysiology of the stress system

CA Stratakis, GP Chrousos - ANNALS-NEW YORK ACADEMY OF …, 1995 - academia.edu
Life exists by maintaining a complex dynamic equilibrium, or homeostasis, that is constantly
challenged by intrinsic or extrinsic adverse forces or stressors.'Stress, a term borrowed from …

Early life stress and trauma: developmental neuroendocrine aspects of prolonged stress system dysregulation

A Agorastos, P Pervanidou, GP Chrousos, G Kolaitis - Hormones, 2018 - Springer
Experience of early life stress (ELS) and trauma is highly prevalent in the general population
and has a high public health impact, as it can trigger a health-related risk cascade and lead …

Hormones, brain and stress.

ER de Kloet - Endocrine regulations, 2003 - europepmc.org
The stress system orchestrates body and brain responses to the environment. This action
exerted by the mediators of the stress system has two modes of operation. The immediate …

Chronic stress: implications for neuronal morphology, function and neurogenesis

M Joëls, H Karst, HJ Krugers, PJ Lucassen - Frontiers in …, 2007 - Elsevier
In normal life, organisms are repeatedly exposed to brief periods of stress, most of which can
be controlled and adequately dealt with. The presently available data indicate that such brief …

Impact of aging on stress-responsive neuroendocrine systems

WA Pedersen, R Wan, MP Mattson - Mechanisms of ageing and …, 2001 - Elsevier
Throughout life organisms are challenged with various physiological and psychological
stressors, and the ability to handle these stressors can have profound effects on the overall …

Mechanisms of stress: a dynamic overview of hormonal and behavioral homeostasis

EO Johnson, TC Kamilaris, GP Chrousos… - … & Biobehavioral Reviews, 1992 - Elsevier
Environmental events, both physical and emotional, can produce stress reactions to widely
varying degrees. Stress can affect many aspects of physiology, and levels of stress …

Physiology and neurobiology of stress and adaptation: central role of the brain

BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …