Lipid rafts is a blanket term used to describe distinct areas in the plasma membrane rich in
certain lipids and proteins and which are thought to perform diverse functions. A large …

Experimental evidence indicates that the mammalian cell membrane is compartmentalized.
A structural feature that supports membrane segmentation implicates assemblies of selected …

Lipid rafts are dynamic assemblies of proteins and lipids that harbour many receptors and
regulatory molecules and so act as a platform for signal transduction. They float freely within …

Engagement of immune receptors by antigen may lead to activation, cell proliferation,
differentiation and effector functions. It has recently been proposed that the initiation and …

Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and
protein composition. They are involved in many aspects of cell biology, including T-cell …

In response to appropriate stimulation, T lymphocytes from systemic lupus erythematosus
(SLE) patients exhibit increased and faster intracellular tyrosine phosphorylation and free …

Lipid rafts, specialized membrane microdomains enriched in sphingolipids and cholesterol,
have been shown to function as signaling platforms in T cells. Surface raft expression is …

The first appearance of lipid rafts, or lipid rafts-like structure, was occasionally observed by
cryo-electronic microscopy in 1980s as cavity, such as caveolae. However, the fully …

During the past decade, the lipid‐raft hypothesis has focused attention on the role of
membrane domains in controlling cellular functions. Among the best‐studied roles of lipid …

The role of lipid rafts in T cell signalling has recently been extensively studied and hotly
debated. In this review we wish to present recent advances in the study of lipid rafts with …