The increasing incidence of bloodstream infections including sepsis is a major challenge in
intensive care units worldwide. However, current diagnostics for pathogen identification …

While fungal infections cause considerable morbidity and mortality, the performance of the
current diagnostic tests for fungal infection is low. Even though fungal metagenomics or …

Background Nanopore Target Sequencing (NTS) represents a novel iteration of gene
sequencing technology; however, its potential utility in the detection of infection in deceased …

Nanopore sequencing has shown the potential to democratize genomic pathogen
surveillance due to its ease of use and low entry cost. However, recent genotyping studies …

Fast and accurate identification of pathogens is an essential task in healthcare settings.
Second-generation sequencing platforms such as Illumina have greatly expanded the …

Identification of bacteria causing tissue infections can be comprehensive and, in the cases of
non-or slow-growing bacteria, near impossible with conventional methods. Performing …

Metagenomic next-generation sequencing (mNGS) is a novel useful strategy that is
increasingly used for pathogens detection in clinic. Some emerging mNGS technologies …

Rapid and accurate pathogen identification is crucial in effectively combating infectious
diseases. However, the current diagnostic tools for bacterial infections predominantly rely on …

Bloodstream infection is a major cause of morbidity and mortality worldwide. We explored
whether MinION nanopore sequencing could accelerate diagnosis, resistance, and …

Cancer patients are at high risk of infections and infection-related mortality; thereby, prompt
diagnosis and precise anti-infectives treatment are critical. This study aimed to evaluate the …