Detection of viral pathogens with multiplex nanopore MinION sequencing: be careful with cross-talk

Y Xu, K Lewandowski, S Lumley, S Pullan… - Frontiers in …, 2018 - frontiersin.org
Metagenomic sequencing with the Oxford Nanopore MinION sequencer offers potential for
point-of-care testing of infectious diseases in clinical settings. To improve cost-effectiveness …

SeqScreen-Nano: a computational platform for streaming, in-field characterization of microbial pathogens

A Balaji, Y Liu, MG Nute, B Hu, A D. Kappell… - Proceedings of the 14th …, 2023 - dl.acm.org
The COVID-19 pandemic forever underscored the need for bio-surveillance platforms
capable of rapidly detecting emerging pathogens. Oxford Nanopore Technology (ONT) …

NanoForms: an integrated server for processing, analysis and assembly of raw sequencing data of microbial genomes, from Oxford Nanopore technology

A Czmil, M Wronski, S Czmil, M Sochacka-Pietal… - PeerJ, 2022 - peerj.com
Background Next Generation Sequencing (NGS) techniques dominate today's landscape of
genetics and genomics research. Though Illumina still dominates worldwide sequencing …

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer

A Benítez-Páez, KJ Portune, Y Sanz - Gigascience, 2016 - academic.oup.com
Background The miniaturised and portable DNA sequencer MinION™ has been released to
the scientific community within the framework of an early access programme to evaluate its …

Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial …

B Bogaerts, A Van den Bossche… - Journal of Clinical …, 2024 - Am Soc Microbiol
Whole-genome sequencing has become the method of choice for bacterial outbreak
investigation, with most clinical and public health laboratories currently routinely using short …

ONTdeCIPHER: an amplicon-based nanopore sequencing pipeline for tracking pathogen variants

E Cherif, FS Thiam, M Salma, G Rivera-Ingraham… - …, 2022 - academic.oup.com
Motivation Amplicon-based nanopore sequencing is increasingly used for molecular
surveillance during epidemics (eg ZIKA, EBOLA) or pandemics (eg SARS-CoV-2). However …

Validation and application of long-read whole-genome sequencing for antimicrobial resistance gene detection and antimicrobial susceptibility testing

T Weinmaier, R Conzemius, Y Bergman… - Antimicrobial agents …, 2023 - Am Soc Microbiol
Next-generation sequencing applications are increasingly used for detection and
characterization of antimicrobial-resistant pathogens in clinical settings. Oxford Nanopore …

Ångström-and nano-scale pore-based nucleic acid sequencing of current and emergent pathogens

BA Shepherd, MRE Tanjil, Y Jeong, B Baloğlu, J Liao… - Mrs …, 2020 - cambridge.org
State-of-the-art nanopore sequencing enables rapid and real-time identification of novel
pathogens, which has wide application in various research areas and is an emerging …

Streaming algorithms for identification pathogens and antibiotic resistance potential from real-time MinION™ sequencing

MD Cao, D Ganesamoorthy, AG Elliott, H Zhang… - …, 2016 - academic.oup.com
Abstract The recently introduced Oxford Nanopore MinION platform generates DNA
sequence data in real-time. This has great potential to shorten the sample-to-results time …

Next-generation sequencing of infectious pathogens

M Gwinn, D MacCannell, GL Armstrong - Jama, 2019 - jamanetwork.com
Next-generation sequencing holds potential for improving clinical and public health
microbiology. 1 In addition to identifying pathogens more rapidly and precisely than …