[HTML][HTML] Pathophysiology of COVID-19: why children fare better than adults?

N Dhochak, T Singhal, SK Kabra, R Lodha - The Indian Journal of …, 2020 - Springer
The world is facing Coronavirus Disease-2019 (COVID-19) pandemic, which is causing a
large number of deaths and burden on intensive care facilities. It is caused by Severe Acute …

[HTML][HTML] COVID-19 in immunosuppressed children

E Nicastro, L Verdoni, LR Bettini, G Zuin… - Frontiers in …, 2021 - frontiersin.org
Following the spread of the SARS-CoV-2 infection and coronavirus disease 2019 (COVID-
19) to a global pandemic, concerns have arisen for the disease impact in at-risk populations …

[HTML][HTML] Why COVID-19 is less frequent and severe in children: a narrative review

R Sinaei, S Pezeshki, S Parvaresh, R Sinaei - World Journal of Pediatrics, 2021 - Springer
Background Despite the streaks of severity, severe acute respiratory syndrome-coronavirus-
2 (SARS-CoV-2) infection is, in general, less frequent and severe in children than in adults …

[HTML][HTML] Understanding COVID-19 in children: immune determinants and post-infection conditions

GA Rotulo, P Palma - Pediatric research, 2023 - nature.com
Coronavirus disease 2019 in children presents with milder clinical manifestations than in
adults. On the other hand, the presence of a wide range of inflammatory manifestations …

Age‐related differences in the immune response could contribute to determine the spectrum of severity of COVID‐19

G Costagliola, E Spada… - … inflammation and disease, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), can present with a wide spectrum of
severity. Elderly patients with cardiac, pulmonary and metabolic comorbidities are more …

Immune response to SARS-CoV-2 in children: A review of the current knowledge

F Filippatos, EB Tatsi, A Michos - Pediatric Investigation, 2021 - mednexus.org
Host immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
especially in children, are still under investigation. Children with coronavirus disease 2019 …

Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections

P Zimmermann, N Curtis - Archives of disease in childhood, 2021 - adc.bmj.com
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …

[HTML][HTML] Coronavirus disease 2019 in children

M Borrelli, A Corcione, F Castellano… - Frontiers in …, 2021 - frontiersin.org
Since its appearance in Wuhan in mid-December 2019, acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) related 19 coronavirus disease (COVID-19) has spread …

Development of child immunity in the context of COVID-19 pandemic

M Kloc, RM Ghobrial, E Kuchar, S Lewicki, JZ Kubiak - Clinical Immunology, 2020 - Elsevier
Children, because of having an immature immune system, are usually more prone than the
adults to the microbial infections and have more severe symptoms, which is especially true …

[HTML][HTML] Current scenario of COVID-19 in pediatric age group and physiology of immune and thymus response

S Rehman, T Majeed, MA Ansari, U Ali, H Sabit… - Saudi journal of …, 2020 - Elsevier
COVID-19 pandemic caused by SARS-CoV-2, continues to manifest with severe acute
respiratory syndrome among the adults, however, it offers a convincing indication of less …