G-protein-coupled receptors (GPCRs) constitute a large family of structurally similar proteins
that respond to a chemically diverse array of physiological and environmental stimulants …

G protein–coupled receptor (GPCR) structural biology has progressed dramatically in the
last decade. There are now over 120 GPCR crystal structures deposited in the Protein Data …

G protein-coupled receptors (GPCR) comprise a diverse superfamily of over 800 proteins
that have gained relevance as biological targets for pharmaceutical drug design. Although …

G protein-coupled receptors (GPCRs) constitute the largest and the most physiologically
important membrane protein family that recognizes a variety of environmental stimuli, and …

G protein-coupled receptors (GPCRs) represent the family of proteins with the highest
impact from social, therapeutic and economic point of view. Today, more than 50% of drug …

G protein-coupled receptors (GPCRs) are a key drug target class. They account for over one-
third of current pharmaceuticals, and both drugs that inhibit and promote receptor function …

G protein-coupled receptors (GPCRs) are targeted by∼ 30–40% of marketed drugs, and
their key roles in normal physiology and in disease demonstrate that an understanding of …

G-protein-coupled receptors (GPCRs) mediate most of our physiological responses to
hormones, neurotransmitters and environmental stimulants, and so have great potential as …

A number of recent technical solutions have led to significant advances in G protein-coupled
receptor (GPCR) structural biology. Apart from a detailed mechanistic view of receptor …

During the past few years, crystallography of G protein–coupled receptors (GPCRs) has
experienced exponential growth, resulting in the determination of the structures of 16 distinct …