Angiotensin-converting enzyme-1 gene insertion/deletion polymorphism may be associated with COVID-19 clinical severity: a prospective cohort study

O Gunal, O Sezer, GU Ustun, CE Ozturk… - Annals of Saudi …, 2021 - annsaudimed.net
BACKGROUND: Angiotensin-converting enzyme (ACE) insertion/deletion (I/D)
polymorphism may play a role in the pathogenesis of coronavirus-19 disease (COVID-19) …

[HTML][HTML] The role of angiotensin converting enzyme 1 insertion/deletion genetic polymorphism in the risk and severity of COVID-19 infection

H Saad, K Jabotian, C Sakr, R Mahfouz, IB Akl… - Frontiers in …, 2021 - frontiersin.org
Background: Individuals infected with the COVID-19 virus present with different symptoms of
varying severity. In addition, not all individuals are infected despite exposure. Risk factors …

Impact of I/D polymorphism of angiotensin-converting enzyme 1 (ACE1) gene on the severity of COVID-19 patients

S Verma, M Abbas, S Verma, FH Khan, ST Raza… - Infection, Genetics and …, 2021 - Elsevier
Severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) has first emerged from
China in December 2019 and causes coronavirus induced disease 19 (COVID-19). Since …

Angiotensin‐converting‐enzyme insertion/deletion polymorphism, ACE activity, and COVID‐19: A rather controversial hypothesis. A case‐control study

A Papadopoulou, PC Fragkou… - Journal of Medical …, 2022 - Wiley Online Library
Accumulating data has shown a contribution of the renin‐angiotensin system in COVID‐19
pathogenesis. The role of angiotensin‐converting enzyme (ACE) insertion (I)/deletion (D) …

The role of ACE1 I/D and ACE2 polymorphism in the outcome of Iranian COVID-19 patients: a case-control study

A Faridzadeh, M Mahmoudi, S Ghaffarpour… - Frontiers in …, 2022 - frontiersin.org
Background: Since the beginning of the pandemic of coronavirus disease 2019 (COVID-19),
many countries have experienced a considerable number of COVID-19 cases and deaths …

Strong association of angiotensin converting enzyme-2 gene insertion/deletion polymorphism with susceptibility to SARS-CoV-2, hypertension, coronary artery …

MM Mir, R Mir, MAA Alghamdi, BA Alsayed… - Journal of personalized …, 2021 - mdpi.com
Background: The ongoing outbreak of SARS-CoV-2 represents a significant challenge to
international health. Several reports have highlighted the importance of ACE2 on the …

Angiotensin-Converting Enzyme (ACE) level, but not ACE gene polymorphism, is associated with prognosis of COVID-19 infection: Implications for diabetes and …

O Elbasan, F Bayram, CD Yazan, T Apaydın… - PloS One, 2023 - journals.plos.org
Background The renin-angiotensin-aldosterone system was shown to be activated in severe
COVID-19 infection. We aimed to investigate the relationship between angiotensin …

[PDF][PDF] The host's angiotensin-converting enzyme polymorphism may explain epidemiological findings in COVID-19 infections

JR Delanghe, MM Speeckaert, ML De Buyzere - Clin Chim Acta, 2020 - academia.edu
The outbreak of the COVID-19 pandemia in 2019/2020 has stimulated research on clinical
laboratory findings in this condition, as evidenced by two recent papers in this journal [1, 2] …

[PDF][PDF] Are angiotensin converting enzyme (ACE1/ACE2) gene variants associated with the clinical severity of COVID-19 pneumonia? A single-center cohort study

S Baştuğ, B Çavdarlı, A Baştuğ… - Anatolian journal of …, 2022 - jag.journalagent.com
Objective: The impact of the coronavirus disease 2019 (COVID-19) pandemic has been
unceasingly ongoing worldwide. Recent bioinformatics analysis and epidemiologic studies …

Ethnic prevalence of angiotensin-converting enzyme deletion (D) polymorphism and COVID-19 risk: rationale for use of angiotensin-converting enzyme inhibitors …

R Sarangarajan, R Winn, MA Kiebish… - Journal of Racial and …, 2021 - Springer
Rationale Hypertension, obesity and diabetes are major risk factors associated with
morbidities underlying COVID-19 infections. Regression analysis correlated presence of …