Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
The outbreak of new coronavirus disease-20119 or COVID-19 infection has become a
global health emergency at the beginning of this year. Currently, no specific vaccines and …

Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …

Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
Abstract Corona virus disease 2019 (COVID-19), is a viral disease caused by novel corona
virus known as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The …

[HTML][HTML] Macrophage activation and cytokine release syndrome in COVID-19: current updates and analysis of repurposed and investigational anti-cytokine drugs

A Iqubal, F Hoda, AK Najmi, SE Haque - Drug Research, 2021 - thieme-connect.com
Coronavirus disease (COVID-19) emerged from Wuhan, has now become pandemic and
the mortality rate is growing exponentially. Clinical complication and fatality rate is much …

Immunomodulation: a broad perspective for patients' survival of COVID-19 infection

CF Adeboboye, BO Oladejo… - European Journal of …, 2020 - journals.tmkarpinski.com
The pathogenesis of the SARS-CoV-2 virus is yet to be well understood. However, patients
with the virus show clinical manifestations which are very similar to those of SARS-CoV and …

Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation

I Amigues, AH Pearlman, A Patel, P Reid… - Expert review of …, 2020 - Taylor & Francis
Introduction: The mortality of coronavirus disease 2019 (COVID-19) is frequently driven by
an injurious immune response characterized by the development of acute respiratory …

Therapeutics for the management of cytokine release syndrome in COVID-19

S Ghosh, S Durgvanshi, SS Han… - Current topics in …, 2023 - ingentaconnect.com
Coronavirus disease (COVID-19) is the greatest pandemic of this era and has affected more
than 10 million people across 213 nations. However, the etiology, management, and …

Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …