Long non-coding RNA UCA1 modulates paclitaxel resistance in breast cancer via miR-613/CDK12 axis

C Liu, F Jiang, X Zhang, X Xu - Cancer Management and Research, 2020 - Taylor & Francis
Background Paclitaxel (PTX) occupies a considerable status in the chemotherapies of
breast cancer (BC), but the drug resistance keeps an obstructive factor of PTX treatment …

[PDF][PDF] Long non-coding RNA UCA1 promotes the progression of paclitaxel resistance in ovarian cancer by regulating the miR-654-5p/SIK2 axis.

ZY Li, XL Wang, Y Dang, XZ Zhu… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: Ovarian cancer (OC) is a common tumor in women, and the development of
chemoresistance is the major obstacle to its treatment. Long non-coding RNAs (LncRNAs) …

UCA1 confers paclitaxel resistance to ovarian cancer through miR-129/ABCB1 axis

J Wang, C Ye, J Liu, Y Hu - Biochemical and biophysical research …, 2018 - Elsevier
Increasing evidence has demonstrated the involvement of dysregulated long non-coding
RNAs (lncRNAs) in chemoresistance acting as potential oncogenes or tumor suppressors in …

Knockdown of long non-coding RNA UCA1 increases the tamoxifen sensitivity of breast cancer cells through inhibition of Wnt/β-catenin pathway

H Liu, G Wang, L Yang, J Qu, Z Yang, X Zhou - PloS one, 2016 - journals.plos.org
Acquired resistance to tamoxifen remains a major obstacle in breast cancer (BC) treatment,
since the underlying mechanism has not been fully elucidated. The long non-coding RNA …

Long non‑coding RNA UCA1 confers tamoxifen resistance in breast cancer endocrinotherapy through regulation of the EZH2/p21 axis and the PI3K/AKT signaling …

Z Li, D Yu, H Li, Y Lv, S Li - … journal of oncology, 2019 - spandidos-publications.com
Tamoxifen is the gold standard for breast cancer endocrinotherapy. However, drug
resistance remains a major limiting factor of tamoxifen treatment. Long non‑coding (lnc) RNA …

[HTML][HTML] Long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) enhances tamoxifen resistance in breast cancer cells via inhibiting mTOR …

C Wu, J Luo - … science monitor: international medical journal of …, 2016 - ncbi.nlm.nih.gov
Long Non-Coding RNA (lncRNA) Urothelial Carcinoma-Associated 1 (UCA1) Enhances
Tamoxifen Resistance in Breast Cancer Cells via Inhibiting mTOR Signaling Pathway - PMC …

LncRNA UCA1 Enhances Cisplatin Resistance by Regulating CYP1B1-mediated Apoptosis via miR-513a-3p in Human Gastric Cancer

H Cheng, G Sharen, Z Wang, J Zhou - Cancer Management and …, 2021 - Taylor & Francis
Background Chemoresistance contributes to treatment failure of gastric cancer (GC) patients
but the molecular mechanism of chemoresistance in GC is still unclear. Long-chain …

LINC00511 knockdown enhances paclitaxel cytotoxicity in breast cancer via regulating miR-29c/CDK6 axis

H Zhang, B Zhao, X Wang, F Zhang, W Yu - Life Sciences, 2019 - Elsevier
Aims Drug resistance is becoming a major clinical challenge to the success of breast cancer
treatment. Compelling evidence has shown the association between the deregulated long …

Long non-coding RNA UCA1 promotes breast cancer by upregulating PTP1B expression via inhibiting miR-206

Y Li, Q Zeng, J Qiu, T Pang, J Xian, X Zhang - Cancer Cell International, 2019 - Springer
Background The long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1)
is involved in various cancers and often functions through microRNAs. The pro-survival …

[HTML][HTML] LncRNA UCA1 promotes cisplatin resistance in gastric cancer via recruiting EZH2 and activating PI3K/AKT pathway

Q Dai, T Zhang, J Pan, C Li - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Background: Drug resistance of cancer cells is one of the major causes of chemotherapy
failure. Recently research demonstrated that long non-coding RNA Urothelial cancer …