A Reznichenko, V Nair, S Eddy, D Fermin, M Tomilo… - Kidney International, 2024 - Elsevier
Current classification of chronic kidney disease (CKD) into stages using indirect systemic measures (estimated glomerular filtration rate (eGFR) and albuminuria) is agnostic to the …
A Tin, A Köttgen - Clinical Journal of the American Society of …, 2020 - journals.lww.com
The past few years have seen major advances in genome-wide association studies (GWAS) of CKD and kidney function–related traits in several areas: increases in sample size from> …
GN Nadkarni, O Gottesman, JG Linneman… - AMIA Annual …, 2014 - ncbi.nlm.nih.gov
Twenty-six million Americans are estimated to have chronic kidney disease (CKD) with increased risk for cardiovascular disease and end stage renal disease. CKD is frequently …
With biomedical research transitioning into data-rich science, machine learning provides a powerful toolkit for extracting knowledge from large-scale biological data sets. The …
AP Morris, TH Le, H Wu, A Akbarov… - Nature …, 2019 - nature.com
Chronic kidney disease (CKD) affects~ 10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association …
S Eddy, LH Mariani, M Kretzler - Nature Reviews Nephrology, 2020 - nature.com
Chronic kidney diseases (CKDs) are currently classified according to their clinical features, associated comorbidities and pattern of injury on biopsy. Even within a given classification …
A Köttgen, C Pattaro - Kidney international, 2020 - kidney-international.org
With increasing incidence and a prev-alence of> 10% among adults worldwide, chronic kidney disease (CKD) represents a major public health issue. 1 CKD can lead to metabolic …
A Köttgen, E Cornec-Le Gall, J Halbritter, K Kiryluk… - Kidney international, 2022 - Elsevier
Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as well as genes for complex kidney diseases that manifest in combination with environmental …
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through trans-ancestry meta-analysis of genome-wide association studies of …