Electronic cigarette aerosol induces significantly less cytotoxicity than tobacco smoke

D Azzopardi, K Patel, T Jaunky… - Toxicology …, 2016 - Taylor & Francis
Electronic cigarettes (E-cigarettes) are a potential means of addressing the harm to public
health caused by tobacco smoking by offering smokers a less harmful means of receiving …

Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems

J Adamson, D Thorne, B Zainuddin, A Baxter… - Chemistry Central …, 2016 - Springer
The diluted aerosols from a cigarette (3R4F) and an e-cigarette (Vype ePen) were compared
in two commercially available in vitro exposure systems: the Borgwaldt RM20S and Vitrocell …

Considerations on dosimetry for in vitro assessment of e-cigarette toxicity

V Forest, C Mercier, J Pourchez - Respiratory Research, 2022 - Springer
Electronic cigarettes (or e-cigarettes) can be used as smoking cessation aid. Some studies
tend to show that they are less hazardous than tobacco cigarettes, even if it does not mean …

A comparative study of electronic cigarette vapor extracts on airway-related cell lines in vitro

LJ Leslie, P Vasanthi Bathrinarayanan… - Inhalation …, 2017 - Taylor & Francis
The use of electronic cigarettes (ECs) is rapidly increasing worldwide; however, scientific
evidence regarding EC cytotoxicity is limited. The aim of this study was to evaluate the acute …

[HTML][HTML] An approach to testing undiluted e-cigarette aerosol in vitro using 3D reconstituted human airway epithelium

E Bishop, L Haswell, J Adamson, S Costigan… - Toxicology In Vitro, 2019 - Elsevier
The data presented here show that to provide an estimate of the relative cytotoxicity and
therefore potency of e-cigarettes, undiluted aerosol techniques can be used. With the …

Comparing the cytotoxicity of electronic cigarette fluids, aerosols and solvents

RZ Behar, Y Wang, P Talbot - Tobacco control, 2018 - tobaccocontrol.bmj.com
Background As thousands of electronic cigarette (e-cigarette) refill fluids continue to be
formulated and distributed, there is a growing need to understand the cytotoxicity of the …

Addressing the challenges of E-cigarette safety profiling by assessment of pulmonary toxicological response in bronchial and alveolar mucosa models

K Ganguly, A Nordström, TA Thimraj, M Rahman… - Scientific reports, 2020 - nature.com
Limited toxicity data on electronic cigarette (ECIG) impede evidence-based policy
recommendations. We compared two popular mixed fruit flavored ECIG-liquids with and …

Basic science of electronic cigarettes: assessment in cell culture and in vivo models

PS Hiemstra, R Bals - Respiratory research, 2016 - Springer
Electronic cigarettes (e-cigarettes, ECIGs) were introduced into the market a decade ago as
an alternative to tobacco smoking. Whether ECIGs are safe and whether they qualify as …

Collecting e‐cigarette aerosols for in vitro applications: A survey of the biomedical literature and opportunities to increase the value of submerged cell culture‐based …

DJ Smart, G Phillips - Journal of Applied Toxicology, 2021 - Wiley Online Library
Electronic nicotine delivery systems (ENDS) are being developed as potentially reduced‐
risk alternatives to the continued use of combustible tobacco products. Because of the …

[HTML][HTML] Modes of Action

DL Eaton, LY Kwan, K Stratton… - … Consequences of E …, 2018 - ncbi.nlm.nih.gov
Although the use of electronic cigarettes has increased steadily since their introduction into
the market about a decade ago, much is unknown about their safety profile. As concluded in …