[HTML][HTML] The developmental brain age is associated with adversity, depression, and functional outcomes among adolescents

V Drobinin, H Van Gestel, CA Helmick… - Biological Psychiatry …, 2022 - Elsevier
Background Most psychiatric disorders emerge in the second decade of life. In the present
study, we examined whether environmental adversity, developmental antecedents, major …

Brain-predicted age associates with psychopathology dimensions in youths

VL Cropley, Y Tian, K Fernando, C Pantelis… - Biological Psychiatry …, 2021 - Elsevier
Background This study aimed to investigate whether dimensional constructs of
psychopathology relate to variation in patterns of brain development and to determine …

[HTML][HTML] Linking brain maturation and puberty during early adolescence using longitudinal brain age prediction in the ABCD cohort

MC Holm, EH Leonardsen, D Beck, A Dahl… - Developmental …, 2023 - Elsevier
The temporal characteristics of adolescent neurodevelopment are shaped by a complex
interplay of genetic, biological, and environmental factors. Using a large longitudinal dataset …

[HTML][HTML] Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms

MJ Lund, D Alnæs, AMG de Lange, OA Andreassen… - NeuroImage: Clinical, 2022 - Elsevier
Objective Magnetic resonance imaging (MRI) has shown that estimated brain age is deviant
from chronological age in various common brain disorders. Brain age estimation could be …

Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort

ML Elliott, DW Belsky, AR Knodt, D Ireland… - Molecular …, 2021 - nature.com
An individual's brainAGE is the difference between chronological age and age predicted
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …

A multidimensional neural maturation index reveals reproducible developmental patterns in children and adolescents

M Truelove-Hill, G Erus, V Bashyam… - Journal of …, 2020 - Soc Neuroscience
Adolescence is a time of extensive neural restructuring, leaving one susceptible to atypical
development. Although neural maturation in humans can be measured using functional and …

[HTML][HTML] Mapping normative trajectories of cognitive function and its relation to psychopathology symptoms and genetic risk in youth

R Kjelkenes, T Wolfers, D Alnæs… - … Psychiatry Global Open …, 2023 - Elsevier
Background Adolescence hosts a sharp increase in the incidence of mental disorders. The
prodromal phases are often characterized by cognitive deficits that predate disease onset by …

Use of machine learning to determine deviance in neuroanatomical maturity associated with future psychosis in youths at clinically high risk

Y Chung, J Addington, CE Bearden… - JAMA …, 2018 - jamanetwork.com
Importance Altered neurodevelopmental trajectories are thought to reflect heterogeneity in
the pathophysiologic characteristics of schizophrenia, but whether neural indicators of these …

Modeling individual differences in brain development

AI Becht, KL Mills - Biological Psychiatry, 2020 - Elsevier
Within the field of developmental cognitive neuroscience, there is an increasing interest in
studying individual differences in human brain development in order to predict mental health …

Assessment of neurobiological mechanisms of cortical thinning during childhood and adolescence and their implications for psychiatric disorders

N Parker, Y Patel, AP Jackowski, PM Pan… - JAMA …, 2020 - jamanetwork.com
Importance Many psychiatric disorders can be conceptualized as disorders of brain
maturation during childhood and adolescence. Discovering the neurobiological …