A deep learning approach to explore the association of age‐related macular degeneration polygenic risk score with retinal optical coherence tomography: A …

A Sendecki, D Ledwoń, J Nycz… - Acta …, 2024 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a complex eye disorder affecting
millions worldwide. This article uses deep learning techniques to investigate the relationship …

Estimating uncertainty of deep neural networks for age-related macular degeneration grading using optical coherence tomography

C de Vente, M van Grinsven… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: Deep convolutional neural networks (CNNs) are increasingly being used for eye
disease screening and diagnosis. Especially the best performing variants, however, are …

Detection of features associated with neovascular age-related macular degeneration in ethnically distinct data sets by an optical coherence tomography: trained deep …

TH Rim, AY Lee, DS Ting, K Teo, BK Betzler… - British Journal of …, 2021 - bjo.bmj.com
Background The ability of deep learning (DL) algorithms to identify eyes with neovascular
age-related macular degeneration (nAMD) from optical coherence tomography (OCT) scans …

Deep-learning-based prediction of late age-related macular degeneration progression

Q Yan, DE Weeks, H Xin, A Swaroop… - Nature machine …, 2020 - nature.com
Both genetic and environmental factors influence the etiology of age-related macular
degeneration (AMD), a leading cause of blindness. AMD severity is primarily measured by …

[HTML][HTML] Genome-wide association studies-based machine learning for prediction of age-related macular degeneration risk

Q Yan, Y Jiang, H Huang, A Swaroop… - … vision science & …, 2021 - iovs.arvojournals.org
Purpose: Because age-related macular degeneration (AMD) is a progressive disorder and
advanced AMD is currently hard to cure, an accurate and informative prediction of a person's …

Modelling the genetic risk in age-related macular degeneration

F Grassmann, LG Fritsche, CN Keilhauer, IM Heid… - PLoS …, 2012 - journals.plos.org
Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease
of the central retina affecting approximately 1 in 30 Caucasians. Besides age and smoking …

Optimized prediction models from fundus imaging and genetics for late age-related macular degeneration

A Govindaiah, A Baten, RT Smith… - Journal of Personalized …, 2021 - mdpi.com
Age-related macular degeneration (AMD) is a leading cause of blindness in the developed
world. In this study, we compare the performance of retinal fundus images and genetic …

Predicting progression to advanced age-related macular degeneration from clinical, genetic, and lifestyle factors using machine learning

S Ajana, A Cougnard-Grégoire, JM Colijn, BMJ Merle… - Ophthalmology, 2021 - Elsevier
Purpose Current prediction models for advanced age-related macular degeneration (AMD)
are based on a restrictive set of risk factors. The objective of this study was to develop a …

Polygenic risk score impact on susceptibility to age-related macular degeneration in polish patients

A Wąsowska, S Teper, E Matczyńska… - Journal of Clinical …, 2022 - mdpi.com
Age-related macular degeneration (AMD) is a common retina degenerative disease with a
complex genetic and environmental background. This study aimed to determine the …

Classifying neovascular age-related macular degeneration with a deep convolutional neural network based on optical coherence tomography images

J Han, S Choi, JI Park, JS Hwang, JM Han, HJ Lee… - Scientific Reports, 2022 - nature.com
Neovascular age-related macular degeneration (nAMD) is among the main causes of visual
impairment worldwide. We built a deep learning model to distinguish the subtypes of nAMD …