Remdesivir for the treatment of hospitalised patients with COVID-19: final results from the DisCoVeRy randomised, controlled, open-label trial

F Ader, M Bouscambert-Duchamp, M Hites… - medRxiv, 2022 - medrxiv.org
Background The antiviral efficacy of remdesivir is still controversial. We aimed at evaluating
its clinical effectiveness in hospitalised patients with COVID-19, with indication of oxygen …

Remdesivir for the Treatment of Hospitalised Patients with COVID-19 (DisCoVeRy): A Randomised, Controlled, Open-Label Trial

F Ader, M Bouscambert-Duchamp, M Hites… - 2021 - papers.ssrn.com
Background: The antiviral efficacy of remdesivir is still controversial. We aimed at evaluating
its clinical effectiveness in patients with COVID-19 requiring oxygen and/or ventilator …

Another step toward final call on Remdesivir efficacy as a treatment for hospitalized COVID-19 patients: a multicenter open-label trial

H Hosseini, A Sadeghi, P Tabarsi, A Etemadimanesh… - MedRxiv, 2021 - medrxiv.org
Introduction After emerging the global pandemic of SARS-CoV2 some preliminary studies
demonstrated the efficacy of antiviral treatments. But shortly thereafter, inconsistencies in the …

[HTML][HTML] Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

Y Wang, D Zhang, G Du, R Du, J Zhao, Y Jin, S Fu… - The lancet, 2020 - thelancet.com
Background No specific antiviral drug has been proven effective for treatment of patients
with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside …

[HTML][HTML] Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3 …

F Ader, M Bouscambert-Duchamp, M Hites… - The Lancet infectious …, 2022 - thelancet.com
Background The antiviral efficacy of remdesivir against SARS-CoV-2 is still controversial.
We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with …

Clinical studies assessing the efficacy, effectiveness and safety of remdesivir in management of COVID‐19: A scoping review

J Pimentel, C Laurie, A Cockcroft… - British journal of …, 2021 - Wiley Online Library
Aims Remdesivir is 1 of the repurposed drugs under investigation to treat patients with
COVID‐19. Clinicians and decision‐makers need a summary of the most recent evidence …

Remdesivir for the treatment of COVID-19: a living systematic review

F Verdugo-Paiva, P Acuña, I Solá, G Rada… - medRxiv, 2020 - medrxiv.org
Objective This living systematic review aims to provide a timely, rigorous and continuously
updated summary of the evidence available on the role of remdesivir in the treatment of …

Remdesivir use in patients with coronavirus COVID-19 disease: a systematic review and meta-analysis of the Chinese Lancet trial with the NIH trial

PE Alexander, J Piticaru, K Lewis, K Aryal, P Thomas… - MedRXiv, 2020 - medrxiv.org
Abstract Background Coronavirus disease 2019 (COVID-19), caused by the novel
coronavirus SARS-CoV-2, has led to significant global mortality and morbidity. Until now, no …

Efficacy and safety of remdesivir for Covid-19 treatment: an analysis of randomized, double-blind, placebo-controlled trials

Y Zhu, Z Teng, L Yang, S Xu, J Liu, Y Teng, Q Hao… - medRxiv, 2020 - medrxiv.org
BACKGROUND Remdesivir, an inhibitor of viral RNA-dependent RNA polymerases, has
been identified as a candidate for COVID-19 treatment. However, the therapeutic effect of …

[引用][C] Efficacy and safety of remdesivir in hospitalized patients with COVID-19: Systematic review and individual patient data meta-analysis of randomized trials

B Speich, C Schönenberger, A Griessbach, P Janiaud… - 2021 - osf.io
This registration describes the protocol of the currently ongoing systematic review and meta-
analysis aiming to use individual patient data (IPD) from all available randomized clinical …