The role of S100B in the interaction between adipocytes and macrophages

A Fujiya, H Nagasaki, Y Seino, T Okawa, J Kato… - …, 2014 - Wiley Online Library
Objective The S100 calcium binding protein B (S100B) implicated in brain inflammation acts
via the receptor of advanced glycation end products (RAGE) and is also secreted from …

Regulation of S100B in white adipose tissue by obesity in mice

LB Buckman, EK Anderson-Baucum, AH Hasty… - Adipocyte, 2014 - Taylor & Francis
S100B is a calcium binding protein found in adipose tissue; however, relatively little is
known about the physiologic regulation or distribution of the protein within this organ. We …

S100A4 protects mice from high-fat diet-induced obesity and inflammation

S Hou, Y Jiao, Q Yuan, J Zhai, T Tian, K Sun… - Laboratory …, 2018 - nature.com
As a member from S100 calcium-binding protein family, S100A4 is ubiquitous and elevated
in tumor progression and metastasis, but its role in regulating obesity has not been well …

The Multifaceted S100B Protein: A Role in Obesity and Diabetes?

F Michetti, G Di Sante, ME Clementi, F Valeriani… - International Journal of …, 2024 - mdpi.com
The S100B protein is abundant in the nervous system, mainly in astrocytes, and is also
present in other districts. Among these, the adipose tissue is a site of concentration for the …

Extracranial sources of S100B do not affect serum levels

N Pham, V Fazio, L Cucullo, Q Teng, P Biberthaler… - PloS one, 2010 - journals.plos.org
S100B, established as prevalent protein of the central nervous system, is a peripheral
biomarker for blood-brain barrier disruption and often also a marker of brain injury. However …

S100 proteins in obesity: liaisons dangereuses

F Riuzzi, S Chiappalupi, C Arcuri, I Giambanco… - Cellular and Molecular …, 2020 - Springer
Obesity is an endemic pathophysiological condition and a comorbidity associated with
hypercholesterolemia, hypertension, cardiovascular disease, type 2 diabetes mellitus, and …

S100B binding to RAGE in microglia stimulates COX-2 expression

R Bianchi, C Adami, I Giambanco… - Journal of Leucocyte …, 2007 - academic.oup.com
Besides exerting regulatory roles within astrocytes, the Ca2+-modulated protein of the EF-
hand type S100B is released into the brain extracellular space, thereby affecting astrocytes …

S100B as a potential biomarker and therapeutic target in multiple sclerosis

A Barateiro, V Afonso, G Santos, JJ Cerqueira… - Molecular …, 2016 - Springer
Multiple sclerosis (MS) pathology is characterized by neuroinflammation and demyelination.
Recently, the inflammatory molecule S100B was identified in cerebrospinal fluid (CSF) and …

S100A16 mediation of weight gain attenuation induced by dietary calcium

R Zhang, W Zhu, X Du, J Xin, Y Xue, Y Zhang, D Li… - Metabolism, 2012 - Elsevier
Dietary calcium influences the regulation of energy metabolism, and weight gain is
attenuated by a high-calcium diet. S100A16 is a novel calcium-binding signaling protein of …

S100B serum levels are closely correlated with body mass index: an important caveat in neuropsychiatric research

J Steiner, K Schiltz, M Walter, MT Wunderlich… - …, 2010 - Elsevier
Elevated blood levels of S100B in neuropsychiatric disorders have so far been mainly
attributed to glial pathologies. However, increases or dysfunction of adipose tissue may be …