The minor allele of ANGPTL8 rs2278426 has a protective effect against CAD in T2DM patients

AG Bilgin, B Ekici, AS Ozuynuk-Ertugrul, AF Erkan… - Gene, 2024 - Elsevier
Background Coronary artery disease (CAD) is the leading cause of death worldwide despite
advanced treatment and diagnosis strategies. Angiopoietin-like protein 8 (ANGPTL8) mainly …

Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits

N Mehta, A Qamar, L Qu, AN Qasim… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Angiopoietin-like protein 3 (ANGPTL3) and 4 (ANGPTL4) are secreted proteins
that inhibit lipoprotein lipase in vitro. Genetic variants at the ANGPTL3 and ANGPTL4 gene …

Increased angiopoietin-like protein 8 levels in patients with type 2 diabetes and cardiovascular disease

Y Huang, C Fang, H Guo, J Hu - Diabetes Research and Clinical Practice, 2016 - Elsevier
In the present study, we recruited 124 patients with type 2 diabetes, among which 22 had a
history of cardiovascular disease (CVD). The study demonstrated that compared with type 2 …

Angiotensin type 1 receptor A1166C polymorphism and systemic lupus erythematosus: correlation with cellular immunity and oxidative stress markers

H Baniamerian, F Bahrehmand, A Vaisi-Raygani… - Lupus, 2017 - journals.sagepub.com
Angiotensin II, one of the rennin–angiotensin system components, is important in the
cardiovascular hemodynamic and plays an important role in the development of …

Tissue-specific epigenetics of atherosclerosis-related ANGPT and ANGPTL genes

KC Ehrlich, M Lacey, M Ehrlich - Epigenomics, 2019 - Taylor & Francis
Aim: To understand tissue-specific regulation of angiopoietin/angiopoietin-like
(ANGPT/ANGPTL) genes (especially the five genes embedded in introns of host genes) and …

Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS

L Su, R Zhai, CC Sheu, DC Gallagher, MN Gong… - Intensive care …, 2009 - Springer
Abstract Objective Angiopoietin-2 (Ang-2) is a potent regulator of vascular permeability and
inflammation in acute lung injury and acute respiratory distress syndrome (ARDS). Genetic …

[HTML][HTML] Angiopoietin-like protein 2 induces synovial inflammation in the facet joint leading to degenerative changes via interleukin-6 secretion

K Sugimoto, T Nakamura, T Tokunaga… - Asian Spine …, 2019 - ncbi.nlm.nih.gov
Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to
Degenerative Changes via Interleukin-6 Secretion - PMC Back to Top Skip to main content NIH …

[HTML][HTML] ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin …

Q Yang, RX Yin, XL Cao, F Huang, YJ Zhou… - Nutrition & …, 2018 - Springer
Background This study aimed to assess the association between the angiopoietin-like
protein 4 gene (ANGPTL4) single nucleotide polymorphisms (SNPs) and serum lipid levels …

ANGPTL8 Gene Polymorphism rs2278426 Is Related to Carotid Intima–Media Thickness in T2DM

C Guo, L Zhao, Y Ding, Z Zhao, C Wang… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Aim ANGPTL8 is a cytokine expressed and secreted by liver and adipose tissue, and is
involved in glucose, lipid, and energy metabolism. Although studies have shown that …

[HTML][HTML] Angiopoietin-2 1087G> A rs3020221 gene polymorphism is associated with in vitro fertilization and embryo transfer outcome

N Ajabi, F Mashayekhi, MA Osalou - Middle East Fertility Society Journal, 2017 - Elsevier
In in vitro fertilization (IVF) the eggs are fertilized in the laboratory. The success of IVF
depends on the angiogenesis. Angiopoetin-2 (ANGPT2) plays a critical role in angiogenesis …