A novel four-dimensional, patient-specific Monte Carlo simulation model of solid tumor
response to chemotherapeutic treatment in vivo is presented. The special case of …

A novel patient individualized, spatiotemporal Monte Carlo simulation model of tumor
response to chemotherapeutic schemes in vivo is presented. Treatment of glioblastoma …

In this paper an advanced, clinically oriented multiscale cancer model of breast tumor
response to chemotherapy is presented. The paradigm of early breast cancer treated by …

Optimizing anticancer therapeutics needs to account for variable drug responses in
heterogeneous cell populations within the tumor as well as in organs of toxicity. To address …

The development of computational models for simulating tumor growth and response to
treatment has gained significant momentum during the last few decades. At the dawn of the …

Glioblastoma multiforme (GBM) is the most malignant form of primary brain tumors known as
gliomas. They proliferate and invade extensively and yield short life expectancies despite …

Adjuvant Temozolomide is considered the front-line Glioblastoma chemotherapeutic
treatment; yet not all patients respond. Latest trends in clinical trials usually refer to …

This paper outlines the major components and function of the technologically integrated
oncosimulator developed primarily within the Advancing Clinico Genomic Trials on Cancer …

Both molecular profiling of tumors and longitudinal tumor size data modeling are relevant
strategies to predict cancer patients' response to treatment. Herein we propose a model of …

A simplified three-dimensional Monte Carlo simulation model of in vitro tumor growth and
response to fractionated radiotherapeutic schemes is presented in this paper. The paper …