Human embryonic stem (ES) cells en-tered the popular lexicon during the political debate of
summer 2001 and the decision by President George Bush to allow federal funding for …

Have a Lot of Potential ducing oligodendrocytes, the ES-derived glial precursor Stem cells
are a major component of the early embryo, cells differentiated to functional …

''Stem cells''and ''Parkinson's disease''are four words that signify some of the most important
translational research in neuroscience. The imagination of scientists has been captured by …

Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …

Significant progress in neural transplantation has been observed over the last several
decades. As a neuroanatomical tool, neural transplantation studies are able to examine the …

Abstract Background and Methods. Patients with Parkinson's disease tend to have a
reduced response to levodopa after 5 to 20 years of therapy, with" on—off" fluctuations …

Current findings suggest that multipotent stem cells may be suitable for cell replacement
therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are …

• In an effort to improve the clinical signs of Parkinson's disease, we have implanted
mesencephalic dopamine cells from a 7-week human embryo into the caudate and putamen …

Dopamine (DA) neurons can be derived from human and primate embryonic stem (ES) cells
in vitro. An ES cell–based replacement therapy for patients with Parkinson's disease …

Human embryonic stem cells (hESCs) have been proposed as a source of dopamine (DA)
neurons for transplantation in Parkinson's disease (PD). We have investigated the effect of in …